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Corinne Grey

Explore the profile of Corinne Grey including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 1174
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Recent Articles
1.
Biot M, Toth A, Brun C, Guichard L, de Massy B, Grey C
Mol Cell . 2024 Apr; 84(10):1826-1841.e5. PMID: 38657614
In meiotic cells, chromosomes are organized as chromatin loop arrays anchored to a protein axis. This organization is essential to regulate meiotic recombination, from DNA double-strand break (DSB) formation to...
2.
Nore A, Juarez-Martinez A, Clement J, Brun C, Diagouraga B, Laroussi H, et al.
Nat Commun . 2022 Nov; 13(1):7048. PMID: 36396648
Meiosis requires the formation of programmed DNA double strand breaks (DSBs), essential for fertility and for generating genetic diversity. DSBs are induced by the catalytic activity of the TOPOVIL complex...
3.
Grey C, de Massy B
Genes Dev . 2022 Jan; 36(1-2):4-6. PMID: 35022326
During meiosis, a molecular program induces DNA double-strand breaks (DSBs) and their repair by homologous recombination. DSBs can be repaired with or without crossovers. ZMM proteins promote the repair toward...
4.
Grey C, de Massy B
Front Cell Dev Biol . 2021 Jun; 9:688878. PMID: 34150782
One of the most fascinating aspects of meiosis is the extensive reorganization of the genome at the prophase of the first meiotic division (prophase I). The first steps of this...
5.
Mihola O, Landa V, Pratto F, Brick K, Kobets T, Kusari F, et al.
BMC Biol . 2021 Apr; 19(1):86. PMID: 33910563
Background: Vertebrate meiotic recombination events are concentrated in regions (hotspots) that display open chromatin marks, such as trimethylation of lysines 4 and 36 of histone 3 (H3K4me3 and H3K36me3). Mouse...
6.
Imai Y, Biot M, Clement J, Teragaki M, Urbach S, Robert T, et al.
Elife . 2020 Oct; 9. PMID: 33047671
Meiotic recombination starts with the formation of DNA double-strand breaks (DSBs) at specific genomic locations that correspond to PRDM9-binding sites. The molecular steps occurring from PRDM9 binding to DSB formation...
7.
Papanikos F, Clement J, Testa E, Ravindranathan R, Grey C, Dereli I, et al.
Mol Cell . 2019 Apr; 74(5):1069-1085.e11. PMID: 31000436
Orderly segregation of chromosomes during meiosis requires that crossovers form between homologous chromosomes by recombination. Programmed DNA double-strand breaks (DSBs) initiate meiotic recombination. We identify ANKRD31 as a key component...
8.
Grey C, Baudat F, de Massy B
PLoS Genet . 2018 Aug; 14(8):e1007479. PMID: 30161134
During meiosis, maternal and paternal chromosomes undergo exchanges by homologous recombination. This is essential for fertility and contributes to genome evolution. In many eukaryotes, sites of meiotic recombination, also called...
9.
Grey C, Clement J, Buard J, LeBlanc B, Gut I, Gut M, et al.
Genome Res . 2017 Mar; 27(4):580-590. PMID: 28336543
In mouse and human meiosis, DNA double-strand breaks (DSBs) initiate homologous recombination and occur at specific sites called hotspots. The localization of these sites is determined by the sequence-specific DNA...
10.
Grey C, Espeut J, Ametsitsi R, Kumar R, Luksza M, Brun C, et al.
Reproduction . 2015 Dec; 151(3):239-51. PMID: 26667018
In sexually reproducing organisms, accurate gametogenesis is crucial for the transmission of genetic material from one generation to the next. This requires the faithful segregation of chromosomes during mitotic and...