Corinne E Hennessy
Overview
Explore the profile of Corinne E Hennessy including associated specialties, affiliations and a list of published articles.
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16
Citations
1552
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Recent Articles
1.
Dobrinskikh E, Hennessy C, Kurche J, Kim E, Estrella A, Cardwell J, et al.
Am J Respir Cell Mol Biol
. 2022 Sep;
68(1):62-74.
PMID: 36108173
The gain-of-function minor allele of the (mucin 5B, oligomeric mucus/gel-forming) promoter (rs35705950) is the strongest risk factor for idiopathic pulmonary fibrosis (IPF), a devastating fibrotic lung disease that leads to...
2.
Okamoto T, Dobrinskikh E, Hennessy C, Liu N, Schwarz M, Evans C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2022 Jul;
323(3):L329-L337.
PMID: 35881171
Previously we have shown that a gain-of-function promoter variant (rs35705950) is the strongest risk factor for the development of idiopathic pulmonary fibrosis. We have also found that Muc5b overexpression reduces...
3.
Stancil I, Michalski J, Hennessy C, Hatakka K, Yang I, Kurche J, et al.
Sci Transl Med
. 2022 Jul;
14(654):eabo5254.
PMID: 35857823
Chronic disease results from the failure of tissues to maintain homeostasis. In the lung, coordinated repair of the epithelium is essential for preserving homeostasis. In animal models and human lung...
4.
Kim E, Mathai S, Stancil I, Ma X, Hernandez-Gutierrez A, Becerra J, et al.
Am J Respir Cell Mol Biol
. 2022 May;
67(2):188-200.
PMID: 35608953
We previously identified a novel molecular subtype of idiopathic pulmonary fibrosis (IPF) defined by increased expression of cilium-associated genes, airway mucin gene , and marker of basal cell airway progenitors....
5.
Dobrinskikh E, Estrella A, Hennessy C, Hara N, Schwarz M, Kurche J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2021 Jun;
321(2):L440-L450.
PMID: 34160296
Idiopathic pulmonary fibrosis (IPF) is an incurable genetic disease that affects 5 million people worldwide. The gain-of-function promoter variant rs35705950 is the dominant genetic risk factor for IPF, yet has...
6.
Morgan L, Jaramillo A, Shenoy S, Raclawska D, Emezienna N, Richardson V, et al.
Nat Commun
. 2021 Jan;
12(1):249.
PMID: 33431872
Airway mucus is essential for lung defense, but excessive mucus in asthma obstructs airflow, leading to severe and potentially fatal outcomes. Current asthma treatments have minimal effects on mucus, and...
7.
Kurche J, Dobrinskikh E, Hennessy C, Huber J, Estrella A, Hancock L, et al.
Am J Respir Cell Mol Biol
. 2019 Oct;
61(4):544-546.
PMID: 31573335
No abstract available.
8.
Hancock L, Hennessy C, Solomon G, Dobrinskikh E, Estrella A, Hara N, et al.
Nat Commun
. 2018 Dec;
9(1):5363.
PMID: 30560893
The gain-of-function MUC5B promoter variant rs35705950 is the dominant risk factor for developing idiopathic pulmonary fibrosis (IPF). Here we show in humans that MUC5B, a mucin thought to be restricted...
9.
Okamoto T, Mathai S, Hennessy C, Hancock L, Walts A, Stefanski A, et al.
Am J Physiol Lung Cell Mol Physiol
. 2018 Mar;
315(1):L1-L10.
PMID: 29565179
The common gain-of-function MUC5B promoter variant ( rs35705950 ) is the strongest risk factor for the development of idiopathic pulmonary fibrosis (IPF). While the role of complement in IPF is...
10.
Yang I, Pedersen B, Liu A, OConnor G, Pillai D, Kattan M, et al.
J Allergy Clin Immunol
. 2016 Oct;
139(5):1478-1488.
PMID: 27745942
Background: Given the strong environmental influence on both epigenetic marks and allergic asthma in children, the epigenetic alterations in respiratory epithelia might provide insight into allergic asthma. Objective: We sought...