Corey R Mandel
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Explore the profile of Corey R Mandel including associated specialties, affiliations and a list of published articles.
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5
Citations
280
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Recent Articles
1.
Cerqueira J, Berthele A, Cree B, Filippi M, Pardo G, Pearson O, et al.
Neurology
. 2025 Jan;
104(4):e210142.
PMID: 39883906
Background And Objectives: Patients with multiple sclerosis (MS) may demonstrate better disease control when treatment is initiated on high-efficacy disease-modifying therapies (DMTs) from onset. This subgroup analysis assessed the long-term...
2.
An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11
Huang J, Liu X, Sun Y, Li Z, Lin M, Hamilton K, et al.
J Biol Chem
. 2023 Feb;
299(4):103047.
PMID: 36822327
Human cleavage and polyadenylation specificity factor (CPSF)73 (also known as CPSF3) is the endoribonuclease that catalyzes the cleavage reaction for the 3'-end processing of pre-mRNAs. The active site of CPSF73...
3.
Mandel C, Tweel B, Tong L
Biochem Biophys Res Commun
. 2009 Jun;
385(4):630-3.
PMID: 19497300
Acyl-CoA thioesterases (ACOTs) catalyze the hydrolysis of CoA esters to free CoA and carboxylic acids and have important functions in lipid metabolism and other cellular processes. Type I ACOTs are...
4.
Mandel C, Tong L
Structure
. 2007 Sep;
15(9):1024-6.
PMID: 17850740
In an elegant study in this issue of Structure, Balbo and Bohm (2007) report the crystal structure of yeast poly(A) polymerase in a ternary complex with its substrate MgATP and...
5.
Mandel C, Kaneko S, Zhang H, Gebauer D, Vethantham V, Manley J, et al.
Nature
. 2006 Nov;
444(7121):953-6.
PMID: 17128255
Most eukaryotic messenger RNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3'-end. Despite the characterization of many proteins that are required for the cleavage reaction,...
6.
Mandel C, Gebauer D, Zhang H, Tong L
Acta Crystallogr Sect F Struct Biol Cryst Commun
. 2006 Oct;
62(Pt 10):1041-5.
PMID: 17012808
The cleavage and polyadenylation specificity factor (CPSF) complex is required for the cleavage and polyadenylation of the 3'-end of messenger RNA precursors in eukaryotes. During structural studies of the 100...