How to Get All "A"s in Polyadenylation
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Biotechnology
Cell Biology
Molecular Biology
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In an elegant study in this issue of Structure, Balbo and Bohm (2007) report the crystal structure of yeast poly(A) polymerase in a ternary complex with its substrate MgATP and the elongating poly(A) tail, providing molecular insights into the mechanism of polyadenylation.
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