Corey M Nemec
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Explore the profile of Corey M Nemec including associated specialties, affiliations and a list of published articles.
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7
Citations
609
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Recent Articles
1.
Duren Z, Lu W, Arthur J, Shah P, Xin J, Meschi F, et al.
Nat Commun
. 2021 Aug;
12(1):4763.
PMID: 34362918
The comparison of gene regulatory networks between diseased versus healthy individuals or between two different treatments is an important scientific problem. Here, we propose sc-compReg as a method for the...
2.
Pervolarakis N, Nguyen Q, Williams J, Gong Y, Gutierrez G, Sun P, et al.
Cell Rep
. 2020 Oct;
33(3):108273.
PMID: 33086071
The mammary epithelial cell (MEC) system is a bilayered ductal epithelium of luminal and basal cells, maintained by a lineage of stem and progenitor populations. Here, we used integrated single-cell...
3.
Satpathy A, Granja J, Yost K, Qi Y, Meschi F, McDermott G, et al.
Nat Biotechnol
. 2019 Aug;
37(8):925-936.
PMID: 31375813
Understanding complex tissues requires single-cell deconstruction of gene regulation with precision and scale. Here, we assess the performance of a massively parallel droplet-based method for mapping transposase-accessible chromatin in single...
4.
Nemec C, Singh A, Ali A, Tseng S, Syal K, Ringelberg K, et al.
Nat Chem Biol
. 2019 Jan;
15(2):123-131.
PMID: 30598543
Phosphorylation of the carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) governs stage-specific interactions with different cellular machines. The CTD consists of YSPTSPS heptad repeats...
5.
Nemec C, Yang F, Gilmore J, Hintermair C, Ho Y, Tseng S, et al.
Proc Natl Acad Sci U S A
. 2017 May;
114(20):E3944-E3953.
PMID: 28465432
The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) orchestrates dynamic recruitment of specific cellular machines during different stages of transcription. Signature phosphorylation patterns of...
6.
Chasman D, Ho Y, Berry D, Nemec C, MacGilvray M, Hose J, et al.
Mol Syst Biol
. 2014 Nov;
10:759.
PMID: 25411400
Stressed cells coordinate a multi-faceted response spanning many levels of physiology. Yet knowledge of the complete stress-activated regulatory network as well as design principles for signal integration remains incomplete. We...
7.
Zhang D, Rodriguez-Molina J, Tietjen J, Nemec C, Ansari A
Genet Res Int
. 2012 May;
2012:347214.
PMID: 22567385
The C-terminal domain (CTD) of RNA polymerase II (Pol II) consists of conserved heptapeptide repeats that function as a binding platform for different protein complexes involved in transcription, RNA processing,...