Constantinos G Broustas
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Explore the profile of Constantinos G Broustas including associated specialties, affiliations and a list of published articles.
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25
Citations
471
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Recent Articles
1.
Mitra D, Armijo G, Ober E, Baker S, Turner H, Broustas C
Gut Microbes
. 2025 Feb;
17(1):2458189.
PMID: 39930324
High-dose radiation exposure results in gastrointestinal (GI) acute radiation syndrome identified by the destruction of mucosal layer, intestinal growth barrier dysfunction, and aberrant inflammatory responses. Further, radiation causes gut microbiome...
2.
Mitra D, Armijo G, Ober E, Baker S, Turner H, Broustas C
bioRxiv
. 2024 Nov;
PMID: 39484519
High-dose radiation exposure results in gastrointestinal (GI) acute radiation syndrome identified by the destruction of mucosal layer, intestinal epithelial barrier dysfunction, and aberrant inflammatory responses. In addition, radiation causes gut...
3.
Wang Q, Bacon B, Taveras M, Phillippi M, Wu X, Broustas C, et al.
Radiat Res
. 2024 Jul;
202(3):541-551.
PMID: 39034036
After a large-scale radiological or nuclear event, hundreds of thousands of people may be exposed to ionizing radiation and require subsequent medical management. Acute exposure to moderate doses (2-6 Gy)...
4.
Broustas C, Mukherjee S, Shuryak I, Taraboletti A, Angdisen J, Ake P, et al.
Radiat Res
. 2023 Jul;
200(3):296-306.
PMID: 37421415
High-dose-radiation exposure in a short period of time leads to radiation syndromes characterized by severe acute and delayed organ-specific injury accompanied by elevated organismal morbidity and mortality. Radiation biodosimetry based...
5.
Broustas C, Shuryak I, Duval A, Amundson S
Cytogenet Genome Res
. 2023 Mar;
163(3-4):197-209.
PMID: 36928338
Blood-based gene expression profiles that can reconstruct radiation exposure are being developed as a practical approach to radiation biodosimetry. However, age and sex could potentially limit the accuracy of the...
6.
Broustas C, Mukherjee S, Pannkuk E, Laiakis E, Fornace A, Amundson S
Radiat Res
. 2022 Mar;
198(1):18-27.
PMID: 35353886
Radiation biodosimetry based on transcriptomic analysis of peripheral blood is a valuable tool to detect radiation exposure after a radiological/nuclear event and obtain useful biological information that could predict tissue...
7.
Panigrahi S, Broustas C, Cuiper P, Virk R, Lieberman H
Cell Signal
. 2021 Jul;
86:110091.
PMID: 34298089
Metastatic progression is the key feature of prostate cancer primarily responsible for mortality caused by this disease. RAD9 is an oncogene for prostate cancer, and the encoded protein enhances metastasis-related...
8.
Broustas C, Duval A, Amundson S
Sci Rep
. 2021 May;
11(1):10177.
PMID: 33986387
As a radiation biodosimetry tool, gene expression profiling is being developed using mouse and human peripheral blood models. The impact of dose, dose-rate, and radiation quality has been studied with...
9.
Zhu A, Hopkins K, Friedman R, Bernstock J, Broustas C, Lieberman H
Carcinogenesis
. 2020 Aug;
42(2):220-231.
PMID: 32780107
Prostate cancer is the second most common type of cancer and the second leading cause of cancer death in American men. RAD9 stabilizes the genome, but prostate cancer cells and...
10.
Broustas C, Duval A, Chaudhary K, Friedman R, Virk R, Lieberman H
Oncogene
. 2020 Jan;
39(12):2467-2477.
PMID: 31980741
Radiotherapy is commonly used to treat a variety of solid human tumors, including localized prostate cancer. However, treatment failure often ensues due to tumor intrinsic or acquired radioresistance. Here we...