Constantine Bitsaktsis
Overview
Explore the profile of Constantine Bitsaktsis including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
431
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0
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Recent Articles
1.
Dias A, Bitsaktsis C, Emdin D, Bosman L, Smith A, Merhi Z
Med Gas Res
. 2023 Apr;
13(4):202-207.
PMID: 37077119
There are limited treatment options for women with severely diminished ovarian reserve (DOR) who experience repeatedly failed in vitro fertilization (IVF) cycles and with persistently thin endometrial lining thickness (EMT)...
2.
Descalzi-Montoya D, Montel R, Smith K, Dziopa E, Darwich A, Yang Z, et al.
Chembiochem
. 2020 Sep;
22(9):1589-1596.
PMID: 32964656
De novo cancer-targeting immunostimulatory peptides have been designed and developed as synthetic antibody mimics. A series of bifunctional peptides incorporating NKp30-binding and NK-cell-activating domains were synthesized as linear dimers and...
3.
Wiedinger K, McCauley J, Bitsaktsis C
Vaccine
. 2020 Jul;
38(35):5634-5646.
PMID: 32646816
Streptococcus pneumoniae (Spn) remains a considerable threat to public health despite the availability of antibiotics and polysaccharide conjugate vaccines. The lack of mucosal immunity in addition to capsular polysaccharide diversity,...
4.
McCauley J, Bitsaktsis C, Cottrell J
J Orthop Res
. 2020 Jan;
38(8):1693-1702.
PMID: 31989683
Fracture repair is a complex process requiring heterotypic interactions between osteogenic cells and immune cells. Recent evidence indicates that macrophages are critically involved in fracture repair. Polarized macrophage populations differentially...
5.
Wiedinger K, Pinho D, Bitsaktsis C
Ther Adv Vaccines
. 2017 Mar;
5(1):15-24.
PMID: 28344805
Backgound: The introduction of the pneumococcal conjugate and polysaccharide vaccines have been valuable tools for combating invasive pneumococcal infection in children and healthy adults. Despite the available vaccination strategies, pneumococcal...
6.
Basava V, Romlein H, Bitsaktsis C, Marzabadi C
Bioorg Med Chem
. 2016 Dec;
25(2):697-705.
PMID: 27979367
The paucity of FDA approved adjuvants renders the synthesis, characterization, and use of new compounds as vaccine adjuvants, a necessity. For this purpose, a novel saccharide analog has been synthesized...
7.
Phillips M, Romeo F, Bitsaktsis C, Sabatino D
Biopolymers
. 2016 May;
106(5):658-72.
PMID: 27216712
The rise of biologics that can stimulate immune responses towards the eradication of tumors has led to the evolution of cancer-based immunotherapy. Representatively, B7H6 has been recently identified as a...
8.
Wiedinger K, Romlein H, Bitsaktsis C
Ther Adv Vaccines
. 2015 Dec;
3(5-6):155-63.
PMID: 26668753
Objectives: Previous studies have demonstrated that intranasal administration of inactivated (fixed) Francisella tularensis (iFt) live vaccine strain (LVS) in conjunction with the mucosal adjuvant, cholera toxin B (CTB), provides full...
9.
Babadjanova Z, Wiedinger K, Gosselin E, Bitsaktsis C
PLoS One
. 2015 Jun;
10(6):e0129981.
PMID: 26114641
Production of pro-inflammatory cytokines by innate immune cells at the early stages of bacterial infection is important for host protection against the pathogen. Many intracellular bacteria, including Francisella tularensis, the...
10.
Franz B, Li Y, Bitsaktsis C, Iglesias B, Pham G, Sunagar R, et al.
J Immunol Res
. 2015 May;
2015:840842.
PMID: 25961064
Fc gamma receptor IIB (FcγRIIB) is the only Fc gamma receptor (FcγR) which negatively regulates the immune response, when engaged by antigen- (Ag-) antibody (Ab) complexes. Thus, the generation of...