Connor R Lamberson
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Explore the profile of Connor R Lamberson including associated specialties, affiliations and a list of published articles.
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6
Citations
189
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Recent Articles
1.
Beavers W, L Rose K, Galligan J, Mitchener M, Rouzer C, Tallman K, et al.
ACS Chem Biol
. 2017 Jun;
12(8):2062-2069.
PMID: 28613820
Determining the impact of lipid electrophile-mediated protein damage that occurs during oxidative stress requires a comprehensive analysis of electrophile targets adducted under pathophysiological conditions. Incorporation of ω-alkynyl linoleic acid into...
2.
Lamberson C, Muchalski H, McDuffee K, Tallman K, Xu L, Porter N
Chem Phys Lipids
. 2017 Feb;
207(Pt B):51-58.
PMID: 28174017
The free radical chain autoxidation of cholesterol and the oxidation products formed, i.e. oxysterols, have been the focus of intensive study for decades. The peroxidation of sterol precursors to cholesterol...
3.
Lamberson C, Xu L, Muchalski H, Montenegro-Burke J, Shmanai V, Bekish A, et al.
J Am Chem Soc
. 2014 Jan;
136(3):838-41.
PMID: 24380377
Substitution of -CD2- at the reactive centers of linoleic and linolenic acids reduces the rate of abstraction of D by a tocopheryl radical by as much as 36-fold, compared to...
4.
Liu W, Xu L, Lamberson C, Merkens L, Steiner R, Elias E, et al.
J Lipid Res
. 2012 Oct;
54(1):244-53.
PMID: 23072947
Smith-Lemli-Opitz syndrome (SLOS) is caused by mutations in the gene encoding 3β-hydroxysterol-Δ(7)-reductase and as a result of this defect, 7-dehydrocholesterol (7-DHC) and 8-dehydrocholesterol (8-DHC) accumulate in the fluids and tissues...
5.
Hill S, Lamberson C, Xu L, To R, Tsui H, Shmanai V, et al.
Free Radic Biol Med
. 2012 Jun;
53(4):893-906.
PMID: 22705367
Polyunsaturated fatty acids (PUFAs) undergo autoxidation and generate reactive carbonyl compounds that are toxic to cells and associated with apoptotic cell death, age-related neurodegenerative diseases, and atherosclerosis. PUFA autoxidation is...
6.
Xu L, Korade Z, Rosado J, Liu W, Lamberson C, Porter N
J Lipid Res
. 2011 Mar;
52(6):1222-1233.
PMID: 21402677
The level of 7-dehydrocholesterol (7-DHC) is elevated in tissues and fluids of Smith-Lemli-Opitz syndrome (SLOS) patients due to defective 7-DHC reductase. Although over a dozen oxysterols have been identified from...