Collin Y Ewald
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Explore the profile of Collin Y Ewald including associated specialties, affiliations and a list of published articles.
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59
Citations
982
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Recent Articles
11.
McGill C, Ewald C, Benayoun B
PLoS One
. 2023 Nov;
18(11):e0294859.
PMID: 38032907
The mammalian innate immune system is sex-dimorphic. Neutrophils are the most abundant leukocyte in humans and represent innate immunity's first line of defense. We previously found that primary mouse bone...
12.
Xu D, Zhou J, Soon W, Kutzli I, Moliere A, Diedrich S, et al.
Nat Commun
. 2023 Oct;
14(1):6806.
PMID: 37884488
Food protein amyloid fibrils have superior technological, nutritional, sensorial, and physical properties compared to native monomers, but there is as yet insufficient understanding of their digestive fate and safety for...
13.
Venz R, Goyala A, Soto-Gamez A, Yenice T, Demaria M, Ewald C
Geroscience
. 2023 Aug;
46(2):1499-1514.
PMID: 37644339
Accumulation of senescent cells accelerates aging and age-related diseases, whereas preventing this accumulation extends the lifespan in mice. A characteristic of senescent cells is increased staining with β-galactosidase (β-gal) ex...
14.
Ewald C, Nystrom A
J Cell Sci
. 2023 Jul;
136(15).
PMID: 37522320
Hemidesmosomes are structural protein complexes localized at the interface of tissues with high mechanical demand and shear forces. Beyond tissue anchoring, hemidesmosomes have emerged as force-modulating structures important for translating...
15.
Ruckstuhl M, Bischof E, Blatch D, Buhayer A, Goldhahn J, Battegay E, et al.
Swiss Med Wkly
. 2023 Jul;
153:40088.
PMID: 37410895
Breakthroughs in medical research in the last century have led to a significant extension of the human lifespan, resulting in a shift towards an elderly population worldwide. Due to the...
16.
Knufinke M, MacArthur M, Ewald C, Mitchell S
Front Aging
. 2023 Jun;
4:1172789.
PMID: 37305228
With an increasing aging population, the burden of age-related diseases magnifies. To alleviate this burden, geroprotection has been an area of intense research focus with the development of pharmacological interventions...
17.
Statzer C, Park J, Ewald C
Aging Dis
. 2023 May;
14(3):670-693.
PMID: 37191434
The biomechanical properties of extracellular matrices (ECM) and their consequences for cellular homeostasis have recently emerged as a driver of aging. Here we review the age-dependent deterioration of ECM in...
18.
Statzer C, Luthria K, Sharma A, Kann M, Ewald C
Biomedicines
. 2023 May;
11(4).
PMID: 37189830
The extracellular matrix (ECM) is earning an increasingly relevant role in many disease states and aging. The analysis of these disease states is possible with the GWAS and PheWAS methodologies,...
19.
Vidovic T, Dakhovnik A, Hrabovskyi O, MacArthur M, Ewald C
Int J Mol Sci
. 2023 May;
24(9).
PMID: 37175557
The mechanistic target of rapamycin (mTOR) kinase is one of the top drug targets for promoting health and lifespan extension. Besides rapamycin, only a few other mTOR inhibitors have been...
20.
Park J, King A, Bjork V, English B, Fedintsev A, Ewald C
Am J Physiol Cell Physiol
. 2023 May;
325(1):C90-C128.
PMID: 37154490
The extracellular matrix (ECM), composed of interlinked proteins outside of cells, is an important component of the human body that helps maintain tissue architecture and cellular homeostasis. As people age,...