Colleen M Sitlani
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Explore the profile of Colleen M Sitlani including associated specialties, affiliations and a list of published articles.
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116
Citations
2773
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Recent Articles
1.
DeConne T, Sitlani C, Decker K, Delaney J, Psaty B, Doyle M, et al.
Am J Physiol Heart Circ Physiol
. 2025 Feb;
PMID: 39930879
Endothelial dysfunction has emerged as a risk factor for many age-related diseases such as cardiovascular disease and Alzheimer's disease and related dementias. T-lymphocytes (T-cells) have been identified as important regulators...
2.
Li X, Chen H, Selvaraj M, Van Buren E, Zhou H, Wang Y, et al.
Nat Comput Sci
. 2025 Feb;
5(2):125-143.
PMID: 39920506
Large-scale whole-genome sequencing (WGS) studies have improved our understanding of the contributions of coding and noncoding rare variants to complex human traits. Leveraging association effect sizes across multiple traits in...
3.
DeConne T, Buzkova P, Pewowaruk R, Delaney J, Psaty B, Tracy R, et al.
Am J Physiol Heart Circ Physiol
. 2024 Nov;
328(1):H113-H119.
PMID: 39589781
Arterial stiffness measured by total pulse wave velocity (T-PWV) is associated with an increased risk of multiple age-related diseases. T-PWV can be described by structural (S-PWV) and load-dependent (LD-PWV) arterial...
4.
Yogeswaran V, Wiggins K, Sitlani C, Ilkhanoff L, Benjamin E, Heckbert S, et al.
JAMA Netw Open
. 2024 Oct;
7(10):e2442319.
PMID: 39476232
Importance: Resting heart rate (RHR) is a widely available measure of cardiovascular fitness that has been associated with several cardiovascular outcomes. RHR has previously been associated with the risk of...
5.
Noordam R, Wang W, Nagarajan P, Wang H, Brown M, Bentley A, et al.
medRxiv
. 2024 Sep;
PMID: 39281768
We performed large-scale genome-wide gene-sleep interaction analyses of lipid levels to identify novel genetic variants underpinning the biomolecular pathways of sleep-associated lipid disturbances and to suggest possible druggable targets. We...
6.
DeConne T, Buzkova P, Pewowaruk R, Delaney J, Psaty B, Tracy R, et al.
medRxiv
. 2024 Aug;
PMID: 39132475
Background: Arterial stiffness measured by total pulse wave velocity (T-PWV) is associated with increased risk of multiple age-related diseases. T-PWV can be described by structural (S-PWV) and load-dependent (LD-PWV) arterial...
7.
Gao J, Giro P, Delaney J, Rasmussen-Torvik L, Taylor K, Thorp E, et al.
ESC Heart Fail
. 2024 Jul;
11(6):4427-4431.
PMID: 39034892
Aims: Intercellular adhesion molecule-1 (ICAM-1) facilitates inflammation via leucocyte recruitment and has been implicated in heart failure with preserved ejection fraction (HFpEF). Approximately 35% of African American individuals carry a...
8.
Fretts A, Jensen P, Sitlani C, Hoofnagle A, Lidgard B, Umans J, et al.
J Am Heart Assoc
. 2024 Jun;
13(13):e032536.
PMID: 38904223
Background: A growing body of research indicates that associations of ceramides and sphingomyelins with mortality depend on the chain length of the fatty acid acylated to the backbone sphingoid base....
9.
Jee Y, Thibord F, Dominguez A, Sept C, Boulier K, Venkateswaran V, et al.
Hum Mol Genet
. 2024 Jun;
33(18):1584-1591.
PMID: 38879759
Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality, with large disparities in incidence rates between Black and White Americans. Polygenic risk scores (PRSs) limited to variants discovered...
10.
Hasser E, Brody J, Bartz T, Thibord F, Li-Gao R, Kauko A, et al.
J Thromb Haemost
. 2024 May;
22(8):2261-2269.
PMID: 38782299
Background: Increased risk of venous thromboembolism (VTE) is a life-threatening side effect for users of oral contraceptives (OCs) or hormone therapy (HT). Objectives: To investigate the potential for genetic predisposition...