Colleen J Winstead
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Explore the profile of Colleen J Winstead including associated specialties, affiliations and a list of published articles.
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13
Citations
398
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Recent Articles
1.
Moldoveanu Z, Suzuki H, Reily C, Satake K, Novak L, Xu N, et al.
J Autoimmun
. 2021 Jan;
118:102593.
PMID: 33508637
Background: IgA nephropathy is thought to be an autoimmune disease wherein galactose-deficient IgA1 (Gd-IgA1) is recognized by IgG autoantibodies, resulting in formation and renal accumulation of nephritogenic immune complexes. Although...
2.
Aliprantis A, Shaw C, Griffin P, Farinola N, Railkar R, Cao X, et al.
Hum Vaccin Immunother
. 2020 Oct;
17(5):1248-1261.
PMID: 33121346
Respiratory Syncytial Virus (RSV) causes lower respiratory tract infections that can be severe and sometimes fatal. The risk for severe RSV infection is highest in infants and older adults. A...
3.
Pham D, Moseley C, Gao M, Savic D, Winstead C, Sun M, et al.
Cell Rep
. 2019 Oct;
29(5):1203-1220.e7.
PMID: 31665634
The basic leucine zipper transcription factor activating transcription factor-like (Batf) contributes to transcriptional programming of multiple effector T cells and is required for T helper 17 (Th17) and T follicular...
4.
DiToro D, Winstead C, Pham D, Witte S, Andargachew R, Singer J, et al.
Science
. 2018 Sep;
361(6407).
PMID: 30213884
In response to infection, naïve CD4 T cells differentiate into two subpopulations: T follicular helper (T) cells, which support B cell antibody production, and non-T cells, which enhance innate immune...
5.
Hahn C, Scott D, Xu X, Roda M, Payne G, Wells J, et al.
Sci Adv
. 2015 Aug;
1(3).
PMID: 26229981
The compartmentalization and transport of proteins and solutes across the endothelium is a critical biologic function altered during inflammation and disease, leading to pathology in multiple disorders. The impact of...
6.
Komocsar W, Blackbourne J, Halstead C, Winstead C, Wierda D
J Immunotoxicol
. 2015 Jan;
13(1):7-19.
PMID: 25585959
The potential immunotoxicity of tabalumab was assessed as a component of standard pre-clinical toxicology studies in cynomolgus monkeys. To evaluate potential tabalumab-associated immunosuppression after antigen challenge, cynomolgus monkeys were administered...
7.
Winstead C
Immunol Lett
. 2014 Aug;
162(2 Pt A):39-47.
PMID: 25149860
The basic functions of the immune system are protection from pathogens and maintenance of tolerance to self. The maintenance of commensal microbiota at mucosal surfaces adds a layer of complexity...
8.
Balasubramani A, Winstead C, Turner H, Janowski K, Harbour S, Shibata Y, et al.
PLoS Genet
. 2014 Jan;
10(1):e1003969.
PMID: 24415943
Differentiation-dependent regulation of the Ifng cytokine gene locus in T helper (Th) cells has emerged as an excellent model for functional study of distal elements that control lineage-specific gene expression....
9.
Winstead C, Weaver C
Cell
. 2013 May;
153(4):739-41.
PMID: 23663773
Defining determinants of T cell fate is central to understanding adaptive immunity and the design of effective vaccines. Tubo et al. demonstrate that intrinsic properties of T cell receptor signaling...
10.
Winstead C, Reilly C, Moon J, Jenkins M, Hamilton S, Jameson S, et al.
J Immunol
. 2010 Apr;
184(9):4749-60.
PMID: 20357265
The functional capacity of the adaptive immune system is dependent on the size and the diversity of the T cell population. In states of lymphopenia, T cells are driven to...