Colin Kern
Overview
Explore the profile of Colin Kern including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
763
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Recent Articles
1.
Heffel M, Zhou J, Zhang Y, Lee D, Hou K, Pastor-Alonso O, et al.
Nature
. 2024 Oct;
635(8038):481-489.
PMID: 39385032
The human hippocampus and prefrontal cortex play critical roles in learning and cognition, yet the dynamic molecular characteristics of their development remain enigmatic. Here we investigated the epigenomic and three-dimensional...
2.
Mah C, Ahmed N, Lopez N, Lam D, Pong A, Monell A, et al.
Genome Biol
. 2024 Apr;
25(1):82.
PMID: 38566187
The spatial organization of molecules in a cell is essential for their functions. While current methods focus on discerning tissue architecture, cell-cell interactions, and spatial expression patterns, they are limited...
3.
Farah E, Hu R, Kern C, Zhang Q, Lu T, Ma Q, et al.
Nature
. 2024 Mar;
627(8005):854-864.
PMID: 38480880
The heart, which is the first organ to develop, is highly dependent on its form to function. However, how diverse cardiac cell types spatially coordinate to create the complex morphological...
4.
Li Y, Preissl S, Miller M, Johnson N, Wang Z, Jiao H, et al.
Science
. 2023 Oct;
382(6667):eadf7044.
PMID: 37824643
Recent advances in single-cell transcriptomics have illuminated the diverse neuronal and glial cell types within the human brain. However, the regulatory programs governing cell identity and function remain unclear. Using...
5.
Smith J, Alfieri J, Anthony N, Arensburger P, Athrey G, Balacco J, et al.
Cytogenet Genome Res
. 2023 Jan;
162(8-9):405-528.
PMID: 36716736
No abstract available.
6.
Jia B, Jussila A, Kern C, Zhu Q, Ren B
Nat Biotechnol
. 2023 Jan;
41(7):1027.
PMID: 36646934
No abstract available.
7.
Jia B, Jussila A, Kern C, Zhu Q, Ren B
Nat Biotechnol
. 2023 Jan;
41(7):1004-1017.
PMID: 36593410
Multiplexed fluorescence in situ hybridization (FISH) is a widely used approach for analyzing three-dimensional genome organization, but it is challenging to derive chromosomal conformations from noisy fluorescence signals, and tracing...
8.
Pan Z, Yao Y, Yin H, Cai Z, Wang Y, Bai L, et al.
Nat Commun
. 2021 Oct;
12(1):5848.
PMID: 34615879
The functional annotation of livestock genomes is crucial for understanding the molecular mechanisms that underpin complex traits of economic importance, adaptive evolution and comparative genomics. Here, we provide the most...
9.
da Silva A, Hauck R, Nociti S, Kern C, Shivaprasad H, Zhou H, et al.
Viruses
. 2021 Aug;
13(8).
PMID: 34452342
Infectious bronchitis virus (IBV) induces respiratory and urogenital disease in chickens. Although IBV replicates in the gastrointestinal tract, enteric lesions are uncommon. We have reported a case of runting-stunting syndrome...
10.
Tong Z, Karawita A, Kern C, Zhou H, Sinclair J, Yan L, et al.
Genes (Basel)
. 2021 Jul;
12(6).
PMID: 34200798
Highly pathogenic avian influenza viruses (HPAIVs) in gallinaceous poultry are associated with viral infection of the endothelium, the induction of a 'cytokine storm, and severe disease. In contrast, in Pekin...