Colin Kern
Overview
Explore the profile of Colin Kern including associated specialties, affiliations and a list of published articles.
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28
Citations
763
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Recent Articles
11.
Mon K, Kern C, Chanthavixay G, Wang Y, Zhou H
Infect Immun
. 2021 May;
89(8):e0073620.
PMID: 34031125
Long-term survival and the persistence of bacteria in the host suggest either host unresponsiveness or induction of an immunological tolerant response to the pathogen. The role of the host immunological...
12.
Huang H, Zhu Q, Jussila A, Han Y, Bintu B, Kern C, et al.
Nat Genet
. 2021 May;
53(7):1064-1074.
PMID: 34002095
Insulators play a critical role in spatiotemporal gene regulation in animals. The evolutionarily conserved CCCTC-binding factor (CTCF) is required for insulator function in mammals, but not all of its binding...
13.
Kern C, Wang Y, Xu X, Pan Z, Halstead M, Chanthavixay G, et al.
Nat Commun
. 2021 Mar;
12(1):1821.
PMID: 33758196
Gene regulatory elements are central drivers of phenotypic variation and thus of critical importance towards understanding the genetics of complex traits. The Functional Annotation of Animal Genomes consortium was formed...
14.
Chanthavixay G, Kern C, Wang Y, Saelao P, Lamont S, Gallardo R, et al.
Front Genet
. 2020 Oct;
11:567812.
PMID: 33101389
Two environmental factors, Newcastle disease and heat stress, are concurrently negatively impacting poultry worldwide and warrant greater attention into developing genetic resistance within chickens. Using two genetically distinct and highly...
15.
Halstead M, Kern C, Saelao P, Wang Y, Chanthavixay G, Medrano J, et al.
BMC Genomics
. 2020 Oct;
21(1):698.
PMID: 33028202
Background: Although considerable progress has been made towards annotating the noncoding portion of the human and mouse genomes, regulatory elements in other species, such as livestock, remain poorly characterized. This...
16.
Wang Y, Saelao P, Kern C, Jin S, Gallardo R, Kelly T, et al.
Genes (Basel)
. 2020 Sep;
11(9).
PMID: 32932855
Heat stress results in reduced productivity, anorexia, and mortality in chickens. The objective of the study was to identify genes and signal pathways associated with heat stress and Newcastle disease...
17.
Kim T, Kern C, Zhou H
Genes (Basel)
. 2020 Apr;
11(4).
PMID: 32252379
Interferon regulatory factor 7 (IRF7) is known as the master transcription factor of the type I interferon response in mammalian species along with IRF3. Yet birds only have IRF7, while...
18.
Mon K, Zhu Y, Chanthavixay G, Kern C, Zhou H
Sci Rep
. 2020 Mar;
10(1):4809.
PMID: 32179754
Intestinal carriage of Salmonella Enteritidis (SE) in the chicken host serves as a reservoir for transmission of Salmonella to humans through the consumption of poultry products. The aim of the...
19.
Kingsley N, Kern C, Creppe C, Hales E, Zhou H, Kalbfleisch T, et al.
Genes (Basel)
. 2019 Dec;
11(1).
PMID: 31861495
One of the primary aims of the Functional Annotation of ANimal Genomes (FAANG) initiative is to characterize tissue-specific regulation within animal genomes. To this end, we used chromatin immunoprecipitation followed...
20.
Bogliotti Y, Chung N, Paulson E, Chitwood J, Halstead M, Kern C, et al.
Biol Reprod
. 2019 Nov;
102(3):671-679.
PMID: 31711115
Full-grown oocytes are transcriptionally quiescent. Following maturation and fertilization, the early stages of embryonic development occur in the absence (or low levels) of transcription that results in a period of...