Colin G Miller
Overview
Explore the profile of Colin G Miller including associated specialties, affiliations and a list of published articles.
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24
Citations
390
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Recent Articles
1.
Talwar D, Miller C, Grossmann J, Szyrwiel L, Schwecke T, Demichev V, et al.
Nat Metab
. 2023 Apr;
5(4):660-676.
PMID: 37024754
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is known to contain an active-site cysteine residue undergoing oxidation in response to hydrogen peroxide, leading to rapid inactivation of the enzyme. Here we show that...
2.
Shearn C, Anderson A, Miller C, Noyd R, Devereaux M, Balasubramaniyan N, et al.
Hepatol Commun
. 2023 Jan;
7(1):e0020.
PMID: 36633484
Background And Aims: Cholestatic liver diseases, including primary sclerosing cholangitis, are characterized by periportal inflammation with progression to hepatic fibrosis and ultimately cirrhosis. We recently reported that the thioredoxin antioxidant...
3.
Shearn C, Anderson A, Devereux M, Orlicky D, Michel C, Petersen D, et al.
PLoS One
. 2022 Nov;
17(11):e0276879.
PMID: 36378690
Inflammatory cholestatic liver diseases, including Primary Sclerosing Cholangitis (PSC), are characterized by periportal inflammation with progression to cirrhosis. The objective of this study was to examine interactions between oxidative stress...
4.
Miller C, Gronbaek H, Virgolini I, Kjaer A, Terve P, Bahri S, et al.
EJNMMI Res
. 2021 Sep;
11(1):84.
PMID: 34487283
Background: Ga-satoreotide trizoxetan is a novel somatostatin receptor antagonist exhibiting higher tumour-to-background ratios and sensitivity compared to Ga-DOTATOC. This randomised, 2 × 3 factorial, phase II study aimed to confirm...
5.
Raunig D, Schmid A, Miller C, Walovitch R, OConnor M, Noever K, et al.
Ther Innov Regul Sci
. 2021 Jul;
55(6):1122-1138.
PMID: 34244987
Though many clinical trials rely on medical image evaluations for primary or key secondary endpoints, the methods to monitor reader performance are all too often mired in the legacy use...
6.
Schmid A, Raunig D, Miller C, Walovitch R, Ford R, OConnor M, et al.
Ther Innov Regul Sci
. 2021 Jul;
55(6):1111-1121.
PMID: 34228319
The debate over human visual perception and how medical images should be interpreted have persisted since X-rays were the only imaging technique available. Concerns over rates of disagreement between expert...
7.
Virgolini I, Bahri S, Kjaer A, Gronbaek H, Iversen P, Carlsen E, et al.
J Nucl Med
. 2021 Jul;
63(3):376-383.
PMID: 34215673
Ga-satoreotide trizoxetan is a novel somatostatin receptor antagonist associated with high sensitivity and reproducibility in neuroendocrine tumor (NET) detection and localization. However, the optimal peptide mass and radioactivity ranges for...
8.
Miller C, Kundert J, Prigge J, Amato J, Perez A, Coppo L, et al.
Antioxidants (Basel)
. 2021 Mar;
10(3).
PMID: 33673577
Cellular oxidants are primarily managed by the thioredoxin reductase-1 (TrxR1)- and glutathione reductase (Gsr)-driven antioxidant systems. In mice having hepatocyte-specific co-disruption of TrxR1 and Gsr (TrxR1/Gsr-null livers), methionine catabolism sustains...
9.
Miller C, Schmidt E
Antioxid Redox Signal
. 2020 Aug;
33(16):1158-1173.
PMID: 32799544
In humans, imbalances in the reduction-oxidation (redox) status of cells are associated with many pathological states. In addition, many therapeutics and prophylactics used as interventions for diverse pathologies either directly...
10.
McLoughlin M, Orlicky D, Prigge J, Krishna P, Talago E, Cavigli I, et al.
Proc Natl Acad Sci U S A
. 2019 May;
116(23):11408-11417.
PMID: 31097586
Thioredoxin reductase-1 (TrxR1)-, glutathione reductase (Gsr)-, and Nrf2 transcription factor-driven antioxidant systems form an integrated network that combats potentially carcinogenic oxidative damage yet also protects cancer cells from oxidative death....