Colin E Delaney
Overview
Explore the profile of Colin E Delaney including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
182
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Delaney C, Methot S, Kalck V, Seebacher J, Hess D, Gasser S, et al.
Nat Struct Mol Biol
. 2022 Apr;
29(5):502.
PMID: 35428846
No abstract available.
2.
Delaney C, Methot S, Kalck V, Seebacher J, Hess D, Gasser S, et al.
Nat Struct Mol Biol
. 2022 Feb;
29(2):85-96.
PMID: 35102319
Transcriptionally silenced heterochromatin bearing methylation of histone H3 on lysine 9 (H3K9me) is critical for maintaining organismal viability and tissue integrity. Here we show that in addition to ensuring H3K9me,...
3.
Methot S, Padeken J, Brancati G, Zeller P, Delaney C, Gaidatzis D, et al.
Nat Cell Biol
. 2021 Nov;
23(11):1163-1175.
PMID: 34737442
The developmental role of histone H3K9 methylation (H3K9me), which typifies heterochromatin, remains unclear. In Caenorhabditis elegans, loss of H3K9me leads to a highly divergent upregulation of genes with tissue and...
4.
Padeken J, Methot S, Zeller P, Delaney C, Kalck V, Gasser S
Genes Dev
. 2020 Dec;
35(1-2):82-101.
PMID: 33303642
The establishment and maintenance of chromatin domains shape the epigenetic memory of a cell, with the methylation of histone H3 lysine 9 (H3K9me) defining transcriptionally silent heterochromatin. We show here...
5.
Li X, Itani O, Haataja L, Dumas K, Yang J, Cha J, et al.
Sci Adv
. 2019 Dec;
5(12):eaax0292.
PMID: 31840061
The mechanistic basis for the biogenesis of peptide hormones and growth factors is poorly understood. Here, we show that the conserved endoplasmic reticulum membrane translocon-associated protein α (TRAPα), also known...
6.
Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65
Delaney C, Methot S, Guidi M, Katic I, Gasser S, Padeken J
J Cell Biol
. 2019 Feb;
218(3):820-838.
PMID: 30737265
The segregation of the genome into accessible euchromatin and histone H3K9-methylated heterochromatin helps silence repetitive elements and tissue-specific genes. In , MET-2, the homologue of mammalian SETDB1, catalyzes H3K9me1 and...
7.
Delaney C, Chen A, Graniel J, Dumas K, Hu P
Development
. 2017 Feb;
144(7):1273-1282.
PMID: 28209779
Animals change developmental fates in response to external cues. In the nematode , unfavorable environmental conditions induce a state of diapause known as dauer by inhibiting the conserved DAF-2 insulin-like...
8.
Dumas K, Delaney C, Flibotte S, Moerman D, Csankovszki G, Hu P
Genetics
. 2013 Jun;
194(3):619-29.
PMID: 23733789
During embryogenesis, an essential process known as dosage compensation is initiated to equalize gene expression from sex chromosomes. Although much is known about how dosage compensation is established, the consequences...
9.
Figueroa-Romero C, Hur J, Bender D, Delaney C, Cataldo M, Smith A, et al.
PLoS One
. 2013 Jan;
7(12):e52672.
PMID: 23300739
Amyotrophic lateral sclerosis (ALS) is a terminal disease involving the progressive degeneration of motor neurons within the motor cortex, brainstem and spinal cord. Most cases are sporadic (sALS) with unknown...