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Colin Birkenbihl

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Articles 19
Citations 204
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Recent Articles
1.
Birkenbihl C, Cuppels M, Boyle R, Klinger H, Langford O, Coughlan G, et al.
Brain Inform . 2025 Jan; 12(1):3. PMID: 39871006
Cognitive resilience (CR) describes the phenomenon of individuals evading cognitive decline despite prominent Alzheimer's disease neuropathology. Operationalization and measurement of this latent construct is non-trivial as it cannot be directly...
2.
Birkenbihl C, de Jong J, Yalchyk I, Frohlich H
Brain Commun . 2024 Dec; 6(6):fcae445. PMID: 39713242
Dementia probably due to Alzheimer's disease is a progressive condition that manifests in cognitive decline and impairs patients' daily life. Affected patients show great heterogeneity in their symptomatic progression, which...
3.
Klinger H, Healy B, Hanseeuw B, Jones R, Boyle R, Townsend D, et al.
Alzheimers Dement . 2024 Oct; 20(12):8728-8738. PMID: 39470175
Introduction: While the influence of cross-sectional β-amyloid (Aβ) on longitudinal changes in cognition is well established, longitudinal change-on-change between Aβ and cognition is less explored. Methods: A series of bivariate...
4.
Birkenbihl C, Cuppels M, Boyle R, Klinger H, Langford O, Coughlan G, et al.
medRxiv . 2024 Sep; PMID: 39228697
Cognitive resilience describes the phenomenon of individuals evading cognitive decline despite prominent Alzheimer's disease neuropathology. Operationalization and measurement of this latent construct is non-trivial as it cannot be directly observed....
5.
Smokovski I, Steinle N, Behnke A, Bhaskar S, Grech G, Richter K, et al.
EPMA J . 2024 Jun; 15(2):149-162. PMID: 38841615
Non-communicable chronic diseases (NCDs) have become a major global health concern. They constitute the leading cause of disabilities, increased morbidity, mortality, and socio-economic disasters worldwide. Medical condition-specific digital biomarker (DB)...
6.
Birkenbihl C, Ahmad A, Massat N, Raschka T, Avbersek A, Downey P, et al.
Sci Rep . 2023 Feb; 13(1):2897. PMID: 36801900
Parkinson's disease (PD) is a highly heterogeneous disease both with respect to arising symptoms and its progression over time. This hampers the design of disease modifying trials for PD as...
7.
Maheux E, Koval I, Ortholand J, Birkenbihl C, Archetti D, Bouteloup V, et al.
Nat Commun . 2023 Feb; 14(1):761. PMID: 36765056
The anticipation of progression of Alzheimer's disease (AD) is crucial for evaluations of secondary prevention measures thought to modify the disease trajectory. However, it is difficult to forecast the natural...
8.
Evsevieva M, Sergeeva O, Mazurakova A, Koklesova L, Prokhorenko-Kolomoytseva I, Shchetinin E, et al.
EPMA J . 2022 Sep; 13(3):351-366. PMID: 36061831
Abstract: Cardiovascular disease remains the leading cause of disease burden globally with far-reaching consequences including enormous socio-economic burden to healthcare and society at large. Cardiovascular health is decisive for reproductive...
9.
Wendland P, Birkenbihl C, Gomez-Freixa M, Sood M, Kschischo M, Frohlich H
NPJ Digit Med . 2022 Aug; 5(1):122. PMID: 35986075
Individual organizations, such as hospitals, pharmaceutical companies, and health insurance providers, are currently limited in their ability to collect data that are fully representative of a disease population. This can,...
10.
Wegner P, Schaaf S, Uebachs M, Domingo-Fernandez D, Salimi Y, Gebel S, et al.
Bioinformatics . 2022 Jun; 38(15):3850-3852. PMID: 35652780
Motivation: The importance of clinical data in understanding the pathophysiology of complex disorders has prompted the launch of multiple initiatives designed to generate patient-level data from various modalities. While these...