Cliff Chen
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Explore the profile of Cliff Chen including associated specialties, affiliations and a list of published articles.
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32
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Recent Articles
11.
Stepien K, Bentley A, Chen C, Dhemech M, Gee E, Orton P, et al.
Front Cardiovasc Med
. 2022 Mar;
9:839391.
PMID: 35321113
Mucopolysaccharidoses (MPS) are a heterogeneous group of disorders that results in the absence or deficiency of lysosomal enzymes, leading to an inappropriate storage of glycosaminoglycans (GAGs) in various tissues of...
12.
Patil S, Wieser M, Chen C, Nelson T, Holliday Z, Roland W
Cureus
. 2022 Feb;
14(1):e21431.
PMID: 35223220
Nontyphoidal (NTS) often cause self-limiting gastroenteritis in adults, known as salmonellosis. Salmonellosis has remained controlled in the United States due to intensive measures. Infrequently, these patients develop bacteremia and local...
13.
Ruan Z, Park P, Wei D, Purandare A, Wan H, OMalley D, et al.
Bioorg Med Chem Lett
. 2021 Jan;
35:127778.
PMID: 33422603
The discovery of a series of substituted diarylether compounds as retinoic acid related orphan receptor γt (RORγt) agonists is described. Compound 1 was identified from deck mining as a RORγt...
14.
Enezate T, Gifft K, Chen C, Omran J, Eniezat M, Reardon M
Cardiovasc Revasc Med
. 2020 Dec;
31:50-54.
PMID: 33339773
Introduction: Acute myocardial infarction (AMI) is a common medical condition in our clinical practice that should be treated with appropriate revascularization in a timely manner. Percutaneous revascularization (PR) has been...
15.
Chen C, Das P, Aytan E, Zhou W, Horowitz J, Satpati B, et al.
ACS Appl Mater Interfaces
. 2020 Aug;
12(34):38744-38750.
PMID: 32805977
The controlled tunability of superconductivity in low-dimensional materials may enable new quantum devices. Particularly in triplet or topological superconductors, tunneling devices such as Josephson junctions, etc., can demonstrate exotic functionalities....
16.
Zhang Y, Chen C, Chen S, Chen X, Shuster D, Puszczalo P, et al.
J Pharmacol Exp Ther
. 2020 Jul;
375(1):139-151.
PMID: 32719071
Organic anion-transporting polypeptide (OATP) 1B induction is an evolving mechanism of drug disposition and interaction. However, there are contradictory reports describing OATP1B expression in hepatocytes and liver biopsies after administration...
17.
Harikrishnan L, Gill P, Kamau M, Qin L, Ruan Z, OMalley D, et al.
Bioorg Med Chem Lett
. 2020 Apr;
30(12):127204.
PMID: 32334911
Substituted benzyloxy aryl compound 2 was identified as an RORγt agonist. Structure based drug design efforts resulted in a potent and selective tricyclic compound 19 which, when administered orally in...
18.
Mostofi A, Evans J, Partington-Smith L, Yu K, Chen C, Silverdale M
NPJ Parkinsons Dis
. 2019 Aug;
5:17.
PMID: 31453317
Both subthalamic nucleus (STN) and caudal zona incerta (cZI) have been implicated as the optimal locus for deep brain stimulation (DBS) in Parkinson's disease (PD). We present a retrospective clinico-anatomical...
19.
Li J, Shi Z, Ortiz V, Aldosary M, Chen C, Aji V, et al.
Phys Rev Lett
. 2019 Jul;
122(21):217204.
PMID: 31283322
We report a longitudinal spin Seebeck effect (SSE) study in epitaxially grown FeF_{2}(110) antiferromagnetic (AFM) thin films with strong uniaxial anisotropy over the temperature range of 3.8-250 K. Both the...
20.
Liu C, Lin J, Moslin R, Tokarski J, Muckelbauer J, Chang C, et al.
ACS Med Chem Lett
. 2019 Mar;
10(3):383-388.
PMID: 30891145
In sharp contrast to a previously reported series of 6-anilino imidazopyridazine based Tyk2 JH2 ligands, 6-((2-oxo-1-substituted-1,2-dihydropyridin-3-yl)amino)imidazo[1,2-]pyridazine analogs were found to display dramatically improved metabolic stability. The N1-substituent on 2-oxo-1,2-dihydropyridine ring...