Clement C Zai
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Explore the profile of Clement C Zai including associated specialties, affiliations and a list of published articles.
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168
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2818
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Recent Articles
11.
Chen C, Howie J, Ebrahimi M, Teymouri K, Woo J, Tiwari A, et al.
Schizophr Res
. 2024 Jul;
271:309-318.
PMID: 39084106
Background: The complement component C4 gene has been identified as a strong marker for schizophrenia (SCZ) risk. The C4 gene has a complex genetic structure consisting of variable structural elements...
12.
Paribello P, Manchia M, Isayeva U, Upali M, Orru D, Pinna F, et al.
Int J Mol Sci
. 2024 Jul;
25(14).
PMID: 39063164
Identifying phenotypes at high risk of suicidal behaviour is a relevant objective of clinical and translational research and can facilitate the identification of possible candidate biomarkers. We probed the potential...
13.
Strom N, Verhulst B, Bacanu S, Cheesman R, Purves K, Gedik H, et al.
medRxiv
. 2024 Jul;
PMID: 39006447
The major anxiety disorders (ANX; including generalized anxiety disorder, panic disorder, and phobias) are highly prevalent, often onset early, persist throughout life, and cause substantial global disability. Although distinct in...
14.
Koyama E, Kant T, Takata A, Kennedy J, Zai C
Transl Psychiatry
. 2024 Jun;
14(1):252.
PMID: 38862490
Excessive and persistent aggressiveness is the most common behavioral problem that leads to psychiatric referrals among children. While half of the variance in childhood aggression is attributed to genetic factors,...
15.
Tomasi J, Lisoway A, Zai C, Zai G, Richter M, Sanches M, et al.
Psychiatry Res
. 2024 Jun;
338:115982.
PMID: 38850888
Given that anxiety disorders (AD) are associated with reduced vagally-mediated heart rate variability (HRV), genetic variants related to HRV may provide insight into anxiety etiology. This study used polygenic risk...
16.
Wang R, Lu J, Herbert D, Lieberman J, Meltzer H, Tiwari A, et al.
Hum Psychopharmacol
. 2024 Apr;
39(4):e2898.
PMID: 38676936
Objectives: The pathology of Tardive Dyskinesia (TD) has yet to be fully understood, but there have been proposed hypotheses for the cause of this condition. Our team previously reported a...
17.
Nievergelt C, Maihofer A, Atkinson E, Chen C, Choi K, Coleman J, et al.
Nat Genet
. 2024 Apr;
56(5):792-808.
PMID: 38637617
Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has thus been limited. We performed...
18.
Isayeva U, Manchia M, Collu R, Primavera D, Deriu L, Caboni E, et al.
Schizophr Res
. 2024 Feb;
266:197-204.
PMID: 38422890
Remission, relapse prevention, and clinical recovery are crucial areas of interest in schizophrenia (SCZ) research. Although SCZ is a chronic disorder with poor overall outcomes, years of research demonstrated that...
19.
Ebrahimi M, Teymouri K, Chen C, Mohiuddin A, Pouget J, Goncalves V, et al.
Schizophrenia (Heidelb)
. 2024 Feb;
10(1):14.
PMID: 38341430
Schizophrenia is a severe mental illness and a major risk factor for suicide, with approximately 50% of schizophrenia patients attempting and 10% dying from suicide. Although genetic components play a...
20.
Jiang X, Zai C, Dimick M, Kennedy J, Young L, Birmaher B, et al.
J Am Acad Child Adolesc Psychiatry
. 2024 Feb;
63(11):1149-1157.
PMID: 38340895
Objective: There is a pronounced gap in knowledge regarding polygenic underpinnings of youth bipolar disorder (BD). This study aimed to compare polygenic risk scores (PRSs) in youth with BD, youth...