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Claudio Cobelli

Explore the profile of Claudio Cobelli including associated specialties, affiliations and a list of published articles. Areas
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Articles 383
Citations 11196
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Recent Articles
1.
Mohan S, Christie H, Laurenti M, Egan A, Bailey K, Cobelli C, et al.
J Clin Endocrinol Metab . 2025 Jan; PMID: 39758010
Context: Defects in insulin secretion and action contribute to the progression of prediabetes to diabetes. However, the contribution of α-cell dysfunction to this process has been unclear. Objective: Understand the...
2.
Schiavon M, Cobelli C, Nair K, Klaus K, Toffolo G, Zhang L, et al.
J Cyst Fibros . 2024 Nov; 24(1):57-65. PMID: 39516143
Background: Cystic Fibrosis (CF) patients historically suffered from undernutrition, infection and inflammation. Insulin insufficiency-related protein catabolism further compromised health. We aimed to determine whether insulin improves protein catabolism in CF...
3.
Vella M, Mohan S, Christie H, Bailey K, Cobelli C, Dalla Man C, et al.
J Endocr Soc . 2024 Jul; 8(8):bvae130. PMID: 39011323
Context: Multiple common genetic variants have been associated with type 2 diabetes, but the mechanism by which they predispose to diabetes is incompletely understood. One such example is variation in...
4.
Zeini M, Laurenti M, Egan A, Muthusamy K, Ramar A, Vella E, et al.
Diabetes . 2024 Jun; 73(9):1440-1446. PMID: 38869455
Article Highlights:
5.
Visentin R, Cobelli C, Sieber J, Dalla Man C
J Diabetes Sci Technol . 2024 Jan; 18(2):309-317. PMID: 38284154
Background: Strict adherence to multiple daily insulin (MDI) therapy is a cornerstone for the achievement of good glucose control in people with advanced type 2 diabetes (T2D). Here, we aim...
6.
Romeres D, Yadav Y, Ruchi F, Carter R, Cobelli C, Basu R, et al.
J Clin Endocrinol Metab . 2024 Jan; 109(9):e1720-e1731. PMID: 38174728
Context: Circulating lactate concentration is an important determinant of exercise tolerance. Objective: This work aimed to determine the role of hyperglycemia on lactate metabolism during exercise in individuals with type...
7.
Ballardini G, Tamadon I, Guarnera D, Al-Haddad H, Iacovacci V, Mariottini F, et al.
Annu Int Conf IEEE Eng Med Biol Soc . 2023 Dec; 2023:1-7. PMID: 38083764
Over the past decade, there has been a growing interest in the development of an artificial pancreas for intraperitoneal insulin delivery. Intraperitoneal implantable pumps guarantee more physiological glycemic control than...
8.
Welch A, Farahani R, Egan A, Laurenti M, Zeini M, Vella M, et al.
J Clin Invest . 2023 Sep; 133(22). PMID: 37751301
BACKGROUNDProglucagon can be processed to glucagon-like peptide1 (GLP-1) within the islet, but its contribution to islet function in humans remains unknown. We sought to understand whether pancreatic GLP-1 alters islet...
9.
Cobelli C, Kovatchev B
J Diabetes Sci Technol . 2023 Sep; 17(6):1493-1505. PMID: 37743740
Arguably, diabetes mellitus is one of the best quantified human conditions. In the past 50 years, the metabolic monitoring technologies progressed from occasional assessment of average glycemia via HbA, through...
10.
Taylor R, Barnes A, Hollingsworth K, Irvine K, Solovyova A, Clark L, et al.
Clin Sci (Lond) . 2023 Aug; 137(16):1333-1346. PMID: 37593846
Weight loss in overweight or obese individuals with Type 2 diabetes (T2D) can normalize hepatic fat metabolism, decrease fatty acid oversupply to β cells and restore normoglycaemia. One in six...