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Claudia Ribeiro de Almeida

Explore the profile of Claudia Ribeiro de Almeida including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 866
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Recent Articles
1.
Pettinati I, Grzechnik P, Ribeiro de Almeida C, Brem J, McDonough M, Dhir S, et al.
Elife . 2018 Dec; 7. PMID: 30507380
Replication-dependent (RD) core histone mRNA produced during S-phase is the only known metazoan protein-coding mRNA presenting a 3' stem-loop instead of the otherwise universal polyA tail. A metallo β-lactamase (MBL)...
2.
Nojima T, Tellier M, Foxwell J, Ribeiro de Almeida C, Tan-Wong S, Dhir S, et al.
Mol Cell . 2018 Nov; 72(6):970-984.e7. PMID: 30449723
Extensive tracts of the mammalian genome that lack protein-coding function are still transcribed into long noncoding RNA. While these lncRNAs are generally short lived, length restricted, and non-polyadenylated, how their...
3.
Dhir A, Dhir S, Borowski L, Jimenez L, Teitell M, Rotig A, et al.
Nature . 2018 Jul; 560(7717):238-242. PMID: 30046113
Mitochondria are descendants of endosymbiotic bacteria and retain essential prokaryotic features such as a compact circular genome. Consequently, in mammals, mitochondrial DNA is subjected to bidirectional transcription that generates overlapping...
4.
Ribeiro de Almeida C, Dhir S, Dhir A, Moghaddam A, Sattentau Q, Meinhart A, et al.
Mol Cell . 2018 May; 70(4):650-662.e8. PMID: 29731414
Class switch recombination (CSR) at the immunoglobulin heavy-chain (IgH) locus is associated with the formation of R-loop structures over switch (S) regions. While these often occur co-transcriptionally between nascent RNA...
5.
Ribeiro de Almeida C, Hendriks R, Stadhouders R
Adv Immunol . 2015 Oct; 128:183-271. PMID: 26477368
The Igκ locus, which is spread over 3Mb of genomic DNA and contains >100 variable (V) genes, serves as an important model system to study long-range chromatin interactions. Here, we...
6.
Stadhouders R, de Bruijn M, Rother M, Yuvaraj S, Ribeiro de Almeida C, Kolovos P, et al.
PLoS Biol . 2014 Feb; 12(2):e1001791. PMID: 24558349
During B cell development, the precursor B cell receptor (pre-BCR) checkpoint is thought to increase immunoglobulin κ light chain (Igκ) locus accessibility to the V(D)J recombinase. Accordingly, pre-B cells lacking...
7.
Nikolic T, Movita D, Lambers M, Ribeiro de Almeida C, Biesta P, Kreefft K, et al.
Cell Mol Immunol . 2013 Sep; 11(1):58-70. PMID: 24013844
Macrophages play an important role in immunity and homeostasis. Upon pathogen recognition via specific receptors, they rapidly induce inflammatory responses. This process is tightly controlled at the transcriptional level. The...
8.
Holwerda S, van de Werken H, Ribeiro de Almeida C, Bergen I, de Bruijn M, Verstegen M, et al.
Nucleic Acids Res . 2013 Jun; 41(14):6905-16. PMID: 23748562
In developing B cells, the immunoglobulin heavy chain (IgH) locus is thought to move from repressive to permissive chromatin compartments to facilitate its scheduled rearrangement. In mature B cells, maintenance...
9.
Ribeiro de Almeida C, Stadhouders R, Thongjuea S, Soler E, Hendriks R
Blood . 2012 Apr; 119(26):6209-18. PMID: 22538856
Regulation of V(D)J recombination events at immunoglobulin (Ig) and T-cell receptor loci in lymphoid cells is complex and achieved via changes in substrate accessibility. Various studies over the last year...
10.
Ribeiro de Almeida C, Stadhouders R, de Bruijn M, Bergen I, Thongjuea S, Lenhard B, et al.
Immunity . 2011 Nov; 35(4):501-13. PMID: 22035845
Regulation of immunoglobulin (Ig) V(D)J gene rearrangement is dependent on higher-order chromatin organization. Here, we studied the in vivo function of the DNA-binding zinc-finger protein CTCF, which regulates interactions between...