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Claudia Gerri

Explore the profile of Claudia Gerri including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 1433
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Recent Articles
1.
Brumm A, McCarthy A, Gerri C, Fallesen T, Woods L, McMahon R, et al.
Dev Cell . 2024 Nov; 60(2):174-185.e5. PMID: 39561779
The human blastocyst contains the pluripotent epiblast from which human embryonic stem cells (hESCs) can be derived. ACTIVIN/NODAL signaling maintains expression of the transcription factor NANOG and in vitro propagation...
2.
Peng Y, Hsiao S, Gupta K, Ruland A, Auernhammer G, Maitz M, et al.
Nat Nanotechnol . 2024 Jan; 19(3):418. PMID: 38297147
No abstract available.
3.
Peng Y, Hsiao S, Gupta K, Ruland A, Auernhammer G, Maitz M, et al.
Nat Nanotechnol . 2023 Aug; 18(12):1463-1473. PMID: 37550574
Three-dimensional cell and organoid cultures rely on the mechanical support of viscoelastic matrices. However, commonly used matrix materials lack control over key cell-instructive properties. Here we report on fully synthetic...
4.
Regin M, Essahib W, Demtschenko A, Dewandre D, David L, Gerri C, et al.
Hum Reprod . 2023 Jun; 38(8):1484-1498. PMID: 37295962
Study Question: Which processes and transcription factors specify the first and second lineage segregation events during human preimplantation development? Summary Answer: Differentiation into trophectoderm (TE) cells can be initiated independently...
5.
Gerri C, McCarthy A, Mei Scott G, Regin M, Stamatiadis P, Brumm S, et al.
Development . 2023 Mar; 150(8). PMID: 36971487
Our understanding of the molecular events driving cell specification in early mammalian development relies mainly on mouse studies, and it remains unclear whether these mechanisms are conserved across mammals, including...
6.
Barry D, Gerri C, Bell D, DAntuono R, Niakan K
J Cell Sci . 2022 May; 135(10). PMID: 35502739
The study of cellular and developmental processes in physiologically relevant three-dimensional (3D) systems facilitates an understanding of mechanisms underlying cell fate, disease and injury. While cutting-edge microscopy technologies permit the...
7.
Bower O, McCarthy A, Lea R, Alanis-Lobato G, Zohren J, Gerri C, et al.
Curr Protoc . 2021 Aug; 1(8):e232. PMID: 34432381
CRISPR-Cas9 mutagenesis facilitates the investigation of gene function in a number of developmental and cellular contexts. Human pluripotent stem cells (hPSCs), either embryonic or induced, are a tractable cellular model...
8.
Ando K, Shih Y, Ebarasi L, Grosse A, Portman D, Chiba A, et al.
Dev Biol . 2021 Jul; 479:11-22. PMID: 34310924
Platelet derived growth factor beta and its receptor, Pdgfrb, play essential roles in the development of vascular mural cells, including pericytes and vascular smooth muscle cells. To determine if this...
9.
Gerri C, Menchero S, Mahadevaiah S, Turner J, Niakan K
Annu Rev Cell Dev Biol . 2020 Oct; 36:411-440. PMID: 33021826
Understanding human embryology has historically relied on comparative approaches using mammalian model organisms. With the advent of low-input methods to investigate genetic and epigenetic mechanisms and efficient techniques to assess...
10.
Gerri C, McCarthy A, Alanis-Lobato G, Demtschenko A, Bruneau A, Loubersac S, et al.
Nature . 2020 Sep; 587(7834):443-447. PMID: 32968278
Current understandings of cell specification in early mammalian pre-implantation development are based mainly on mouse studies. The first lineage differentiation event occurs at the morula stage, with outer cells initiating...