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Claudette St Croix

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Articles 46
Citations 2121
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Recent Articles
1.
Gilmer G, Iijima H, Hettinger Z, Jackson N, Bergmann J, Bean A, et al.
Nat Aging . 2025 Jan; 5(1):65-86. PMID: 39820791
Female individuals who are post-menopausal present with higher incidence of knee osteoarthritis (KOA) than male counterparts; however, the mechanisms underlying this disparity are unknown. The most commonly used preclinical models...
2.
Hwang H, Berry B, St Croix C, Wojtovich A, Shiva S, Ghazi A
bioRxiv . 2024 Oct; PMID: 39386500
Reproductive status influences metabolism and health across lifespan in diverse ways and mitochondrial function playing a critical role in mediating this relationship. Using the germline ablation model, we investigated the...
3.
Frisbie L, Pressimone C, Dyer E, Baruwal R, Garcia G, St Croix C, et al.
Cell Rep . 2024 Jul; 43(8):114551. PMID: 39067022
Ovarian cancer is characterized by early metastatic spread. This study demonstrates that carcinoma-associated mesenchymal stromal cells (CA-MSCs) enhance metastasis by increasing tumor cell heterogeneity through mitochondrial donation. CA-MSC mitochondrial donation...
4.
Yamada K, St Croix C, Stolz D, Tyurina Y, Tyurin V, Bradley L, et al.
Nat Commun . 2024 Jul; 15(1):5818. PMID: 38987265
A stable mitochondrial pool is crucial for healthy cell function and survival. Altered redox biology can adversely affect mitochondria through induction of a variety of cell death and survival pathways,...
5.
Nguyen Q, Rao K, Sembrat J, St Croix C, Kaufman B, Scott I, et al.
J Mol Cell Cardiol . 2024 Apr; 190:79-81. PMID: 38608599
No abstract available.
6.
Nolfi-Donegan D, Annarapu G, St Croix C, Calderon M, Hillery C, Shiva S
JCI Insight . 2024 Mar; 9(5). PMID: 38456510
Thrombosis and inflammation are intimately linked and synergistically contribute to the pathogenesis of numerous thromboinflammatory diseases, including sickle cell disease (SCD). While platelets are central to thrombogenesis and inflammation, the...
7.
Undamatla R, Fagunloye O, Chen J, Edmunds L, Murali A, Mills A, et al.
Res Sq . 2023 Jan; PMID: 36711642
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of pathologies that includes steatosis, steatohepatitis (NASH) and fibrosis and is strongly associated with insulin resistance and type 2 diabetes. Changes in...
8.
Heiman P, Mohsen A, Karunanidhi A, St Croix C, Watkins S, Koppes E, et al.
Sci Rep . 2022 Feb; 12(1):3045. PMID: 35197517
Transport and Golgi Organization protein 2 Homolog (TANGO2)-related disease is an autosomal recessive disorder caused by mutations in the TANGO2 gene. Symptoms typically manifest in early childhood and include developmental...
9.
Koudelka A, Cechova V, Rojas M, Mitash N, Bondonese A, St Croix C, et al.
Redox Biol . 2022 Feb; 50:102226. PMID: 35150970
Tissue fibrosis occurs in response to dysregulated metabolism, pro-inflammatory signaling and tissue repair reactions. For example, lungs exposed to environmental toxins, cancer therapies, chronic inflammation and other stimuli manifest a...
10.
Jin M, Watkins S, Larriba Y, Wallace C, St Croix C, Zhou X, et al.
J Allergy Clin Immunol . 2022 Jan; 149(3):1132-1133. PMID: 35000771
No abstract available.