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Clarice X Lim

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Recent Articles
1.
Reddy K, Bizymi N, Schweikert A, Ananth S, Lim C, Lodge K, et al.
ERJ Open Res . 2024 Apr; 10(2). PMID: 38686182
Early career members of Assembly 3 (Basic and Translational Sciences) of the European Respiratory Society (ERS) summarise the key messages discussed during six selected sessions that took place at the...
2.
Lim C, Redl A, Kleissl L, Pandey R, Mayerhofer C, El Jammal T, et al.
Am J Respir Crit Care Med . 2024 Feb; 209(9):1152-1164. PMID: 38353578
Chronic sarcoidosis is a complex granulomatous disease with limited treatment options that can progress over time. Understanding the molecular pathways contributing to disease would aid in new therapeutic development. To...
3.
Bueno-Beti C, Lim C, Protonotarios A, Szabo P, Westaby J, Mazic M, et al.
J Am Heart Assoc . 2023 Sep; 12(19):e030478. PMID: 37750561
Background Sarcoidosis is an inflammatory, granulomatous disease of unknown cause affecting multiple organs, including the heart. Untreated, unresolved granulomatous inflammation can lead to cardiac fibrosis, arrhythmias, and eventually heart failure....
4.
Celada S, Lim C, Carisey A, Ochsner S, Arce Deza C, Rexie P, et al.
Sci Transl Med . 2023 Sep; 15(713):eade2581. PMID: 37703351
Sarcoidosis is an interstitial lung disease (ILD) characterized by interferon-γ (IFN-γ) and T-box expressed in T cells (TBET) dysregulation. Although one-third of patients progress from granulomatous inflammation to severe lung...
5.
Krausgruber T, Redl A, Barreca D, Doberer K, Romanovskaia D, Dobnikar L, et al.
Immunity . 2023 Feb; 56(2):289-306.e7. PMID: 36750099
Granulomas are lumps of immune cells that can form in various organs. Most granulomas appear unstructured, yet they have some resemblance to lymphoid organs. To better understand granuloma formation, we...
6.
Lim C, Weichhart T
J Exp Med . 2021 Sep; 218(10). PMID: 34515726
Löfgren's syndrome is an acute form of sarcoidosis that is characterized by the activation of CD4+ T helper cells. In this issue of JEM, Greaves et al. (2021. J. Exp....
7.
Lim C, Lee B, Geiger O, Passegger C, Beitzinger M, Romberger J, et al.
Cell Rep . 2020 Mar; 30(11):3793-3805.e5. PMID: 32187550
DC-SIGN monocyte-derived dendritic cells (mo-DCs) play important roles in bacterial infections and inflammatory diseases, but the factors regulating their differentiation and proinflammatory status remain poorly defined. Here, we identify a...
8.
Pacheco Y, Lim C, Weichhart T, Valeyre D, Bentaher A, Calender A
Trends Immunol . 2020 Mar; 41(4):286-299. PMID: 32122794
Sarcoidosis is an enigmatic multisystem disease characterized by the development and accumulation of granulomas: a compact collection of macrophages that have differentiated into epithelioid cells and which are associated with...
9.
Calender A, Lim C, Weichhart T, Buisson A, Besnard V, Rollat-Farnier P, et al.
Eur Respir J . 2019 Apr; 54(2). PMID: 31023854
No abstract available.
10.
Calender A, Rollat Farnier P, Buisson A, Pinson S, Bentaher A, Lebecque S, et al.
BMC Med Genomics . 2018 Mar; 11(1):23. PMID: 29510755
Background: Sarcoidosis (OMIM 181000) is a multi-systemic granulomatous disorder of unknown origin. Despite multiple genome-wide association (GWAS) studies, no major pathogenic pathways have been identified to date. To find out...