Clara Tenkerian
Overview
Explore the profile of Clara Tenkerian including associated specialties, affiliations and a list of published articles.
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8
Citations
122
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Recent Articles
1.
Regensburger D, Tenkerian C, Purzer V, Schmid B, Wohlfahrt T, Stolzer I, et al.
Inflamm Bowel Dis
. 2021 Jan;
27(9):1491-1502.
PMID: 33393634
Background: The understanding of vascular plasticity is key to defining the role of blood vessels in physiologic and pathogenic processes. In the present study, the impact of the vascular quiescence...
2.
Klingler A, Regensburger D, Tenkerian C, Britzen-Laurent N, Hartmann A, Sturzl M, et al.
PLoS One
. 2020 May;
15(5):e0233422.
PMID: 32437418
SPARCL1 is a matricellular protein with anti-adhesive, anti-proliferative and anti-tumorigenic functions and is frequently downregulated in tumors such as colorectal carcinoma or non-small cell lung cancer. Studies have identified SPARCL1...
3.
Unterer B, Wiesmann V, Gunasekaran M, Sticht H, Tenkerian C, Behrens J, et al.
Biochem J
. 2018 Aug;
475(18):2955-2967.
PMID: 30120107
Interferon-gamma (IFN-γ) is a pleiotropic cytokine that exerts important functions in inflammation, infectious diseases, and cancer. The large GTPase human guanylate-binding protein 1 (GBP-1) is among the most strongly IFN-γ-induced...
4.
Naschberger E, Regensburger D, Tenkerian C, Langheinrich M, Engel F, Geppert C, et al.
J Vis Exp
. 2018 Apr;
(134).
PMID: 29683458
Primary cells isolated from human carcinomas are valuable tools to identify pathogenic mechanisms contributing to disease development and progression. In particular, endothelial cells (EC) constituting the inner surface of vessels,...
5.
Krishnamoorthy J, Tenkerian C, Gupta J, Ghaddar N, Wang S, Darini C, et al.
Cell Death Dis
. 2018 Feb;
9(3):254.
PMID: 29449538
Oxidative stress determines cell fate through several mechanisms, among which regulation of mRNA translation by the phosphorylation of the alpha (α) subunit of the translation initiation factor eIF2α at serine...
6.
Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al.
Nat Commun
. 2016 Apr;
7:11127.
PMID: 27040916
Ternary complex (TC) and eIF4F complex assembly are the two major rate-limiting steps in translation initiation regulated by eIF2α phosphorylation and the mTOR/4E-BP pathway, respectively. How TC and eIF4F assembly...
7.
Tenkerian C, Krishnamoorthy J, Mounir Z, Kazimierczak U, Khoutorsky A, Staschke K, et al.
Mol Cancer Res
. 2015 Jul;
13(10):1377-88.
PMID: 26130148
Unlabelled: The mTOR nucleates two complexes, namely mTOR complex 1 and 2 (mTORC1 and mTORC2), which are implicated in cell growth, survival, metabolism, and cancer. Phosphorylation of the α-subunit of...
8.
Tenkerian C, El-Sibai M, Daher C, Mroueh M
Evid Based Complement Alternat Med
. 2015 Feb;
2015:161720.
PMID: 25694787
Tragopogon porrifolius (Asteraceae), commonly referred to as white salsify, is an edible herb used in Lebanese folk medicine to treat cancer and liver dysfunction. In this study, we investigated the...