Ivan Topisirovic
Overview
Explore the profile of Ivan Topisirovic including associated specialties, affiliations and a list of published articles.
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Articles
131
Citations
9960
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Recent Articles
1.
Loughran G, Andreev D, Terenin I, Namy O, Mikl M, Yordanova M, et al.
Nat Struct Mol Biol
. 2025 Mar;
PMID: 40033152
Dual reporters encoding two distinct proteins within the same mRNA have had a crucial role in identifying and characterizing unconventional mechanisms of eukaryotic translation. These mechanisms include initiation via internal...
2.
Bujisic B, Lee H, Xu L, Weissbein U, Rivera C, Topisirovic I, et al.
Nat Commun
. 2025 Feb;
16(1):1630.
PMID: 39952919
Non-coding 7SL RNA is an ancestor to mammalian Alu and B1 SINE RNAs and is thought to function exclusively within the Signal Recognition Particle (SRP), aiding in the translocation of...
3.
Feng Y, Grotegut S, Jovanovic P, Gandin V, Olson S, Murad R, et al.
Front Pharmacol
. 2025 Jan;
15:1528449.
PMID: 39749209
[This corrects the article DOI: 10.3389/fphar.2022.1029093.].
4.
Feng Y, Radaeva M, Amiri M, Deshpande A, Olson S, Jovanovic P, et al.
bioRxiv
. 2024 Nov;
PMID: 39605602
Elevated expression of components of eIF4F translation initiation complex has been documented in cancer, resulting in enhanced translation of mRNAs encoding pro-tumorigenic factors, including oncogenic proteins. We previously identified SBI-756,...
5.
Herrmannova A, Jelinek J, Pospisilova K, Kerenyi F, Vomastek T, Watt K, et al.
Elife
. 2024 Nov;
13.
PMID: 39495207
Protein synthesis plays a major role in homeostasis and when dysregulated leads to various pathologies including cancer. To this end, imbalanced expression of eukaryotic translation initiation factors (eIFs) is not...
6.
Park J, Wu J, Szkop K, Jeong J, Jovanovic P, Husmann D, et al.
Nature
. 2024 Jul;
632(8025):656-663.
PMID: 39048817
Dysregulated transcription due to disruption in histone lysine methylation dynamics is an established contributor to tumorigenesis. However, whether analogous pathologic epigenetic mechanisms act directly on the ribosome to advance oncogenesis...
7.
El Bakkouri Y, Chidiac R, Delisle C, Corriveau J, Cagnone G, Gaonach-Lovejoy V, et al.
Nat Commun
. 2024 May;
15(1):4405.
PMID: 38782923
Zonula occludens-1 (ZO-1) is involved in the regulation of cell-cell junctions between endothelial cells (ECs). Here we identify the ZO-1 protein interactome and uncover ZO-1 interactions with RNA-binding proteins that...
8.
Huang F, Goncalves C, Bartish M, Remy-Sarrazin J, Issa M, Cordeiro B, et al.
J Clin Invest
. 2024 May;
134(9).
PMID: 38690739
No abstract available.
9.
Zhan Y, Guo J, Yang W, Goncalves C, Rzymski T, Dreas A, et al.
J Clin Invest
. 2024 Apr;
134(8).
PMID: 38618965
No abstract available.
10.
Kim H, Lebeau B, Papadopoli D, Jovanovic P, Russo M, Avizonis D, et al.
iScience
. 2024 Mar;
27(3):109188.
PMID: 38433910
Emerging data suggest a significant cross-talk between metabolic and epigenetic programs. However, the relationship between the mechanistic target of rapamycin (mTOR), which is a pivotal metabolic regulator, and epigenetic modifications...