Clair Baldock
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Explore the profile of Clair Baldock including associated specialties, affiliations and a list of published articles.
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94
Citations
2064
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Recent Articles
11.
Mead T, Martin D, Wang L, Cain S, Gulec C, Cahill E, et al.
Elife
. 2022 May;
11.
PMID: 35503090
The embryonic extracellular matrix (ECM) undergoes transition to mature ECM as development progresses, yet few mechanisms ensuring ECM proteostasis during this period are known. Fibrillin microfibrils are macromolecular ECM complexes...
12.
Zhang X, Alanazi Y, Jowitt T, Roseman A, Baldock C
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35456902
As essential components of our connective tissues, elastic fibres give tissues such as major blood vessels, skin and the lungs their elasticity. Their formation is complex and co-ordinately regulated by...
13.
Lockhart-Cairns M, Cain S, Dajani R, Steer R, Thomson J, Alanazi Y, et al.
Matrix Biol
. 2022 Feb;
107:24-39.
PMID: 35122964
TGFβ superfamily members are potent growth factors in the extracellular matrix with essential roles in all aspects of cellular behaviour. Latent TGFβ binding proteins (LTBPs) are co-expressed with TGFβ, essential...
14.
Alanazi Y, Lockhart-Cairns M, Cain S, Jowitt T, Weiss A, Baldock C
Front Genet
. 2021 Sep;
12:706662.
PMID: 34539739
Latent TGFβ binding protein-4 (LTBP4) is a multi-domain glycoprotein, essential for regulating the extracellular bioavailability of TGFβ and assembly of elastic fibre proteins, fibrillin-1 and tropoelastin. LTBP4 mutations are linked...
15.
Correns A, Zimmermann L, Baldock C, Sengle G
Matrix Biol Plus
. 2021 Aug;
11:100071.
PMID: 34435185
Bone morphogenic proteins (BMPs) are important growth regulators in embryogenesis and postnatal homeostasis. Their tight regulation is crucial for successful embryonic development as well as tissue homeostasis in the adult...
16.
Singh M, Becker M, Godwin A, Baldock C
Matrix Biol Plus
. 2021 Aug;
12:100078.
PMID: 34355160
Elastic tissues owe their functional properties to the composition of their extracellular matrices, particularly the range of extracellular, multidomain extensible elastic fibre and microfibrillar proteins. These proteins include elastin, fibrillin,...
17.
Ozsvar J, Yang C, Cain S, Baldock C, Tarakanova A, Weiss A
Front Bioeng Biotechnol
. 2021 Mar;
9:643110.
PMID: 33718344
Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience, and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic...
18.
Furlan A, Spanou C, Godwin A, Wohl A, Zimmermann L, Imhof T, et al.
FASEB J
. 2021 Feb;
35(3):e21353.
PMID: 33629769
Since their discovery as pluripotent cytokines extractable from bone matrix, it has been speculated how bone morphogenetic proteins (BMPs) become released and activated from the extracellular matrix (ECM). In contrast...
19.
Peeters S, Decramer A, Cain S, Houpt P, Verstreken F, Noyez J, et al.
J Med Genet
. 2020 Sep;
58(11):778-782.
PMID: 32900841
Background: Although carpal tunnel syndrome (CTS) is the most common form of peripheral entrapment neuropathy, its pathogenesis remains largely unknown. An estimated heritability index of 0.46 and an increased familial...
20.
Lockhart-Cairns M, Newandee H, Thomson J, Weiss A, Baldock C, Tarakanova A
J Mol Biol
. 2020 Sep;
432(21):5736-5751.
PMID: 32898582
Elastic fibres are essential components of all mammalian elastic tissues such as blood vessels, lung and skin, and are critically important for the mechanical properties they endow. The main components...