Cindrilla Chumduri
Overview
Explore the profile of Cindrilla Chumduri including associated specialties, affiliations and a list of published articles.
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21
Citations
359
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Recent Articles
1.
Prakash P, Kumar N, Gurumurthy R, Chumduri C
Sci Data
. 2024 Nov;
11(1):1238.
PMID: 39550363
Gastroesophageal disorders and cancers impose a significant global burden. Particularly, the prevalence of esophageal adenocarcinoma (EAC) has increased dramatically in recent years. Barrett's esophagus, a precursor of EAC, features a...
2.
Kumar N, Prakash P, Wentland C, Kurian S, Jethva G, Brinkmann V, et al.
Nat Commun
. 2024 Apr;
15(1):3064.
PMID: 38594232
The gastroesophageal squamocolumnar junction (GE-SCJ) is a critical tissue interface between the esophagus and stomach, with significant relevance in the pathophysiology of gastrointestinal diseases. Despite this, the molecular mechanisms underlying...
3.
Gurumurthy R, Kumar N, Chumduri C
Methods Mol Biol
. 2023 Dec;
2749:109-121.
PMID: 38133779
The ectocervix acts as a multilayered defense barrier, protecting the female reproductive system from external pathogens and supporting fertility and pregnancy. To understand the complex cellular and molecular mechanisms of...
4.
Dong J, Holthaus D, Peters C, Koster S, Ehsani M, Quevedo-Olmos A, et al.
Front Immunol
. 2023 Dec;
14:1281646.
PMID: 38090581
Cervical cancer is a leading cause of death among women globally, primarily driven by high-risk papillomaviruses. However, the effectiveness of chemotherapy is limited, underscoring the potential of personalized immunotherapies. Patient-derived...
5.
Gurumurthy R, Pleissner K, Chumduri C, Meyer T, Maurer A
BMC Bioinformatics
. 2022 Oct;
23(1):440.
PMID: 36271357
Background: High-content screening (HCS) experiments generate complex data from multiple object features for each cell within a treated population. Usually, these data are analyzed by using population-averaged values of the...
6.
Gurumurthy R, Koster S, Kumar N, Meyer T, Chumduri C
Nat Protoc
. 2022 May;
17(7):1658-1690.
PMID: 35546639
The cervix is the gateway to the upper female reproductive tract, connecting the uterus and vagina. It plays crucial roles in fertility and pregnancy maintenance from onset until delivery of...
7.
Koster S, Gurumurthy R, Kumar N, Prakash P, Dhanraj J, Bayer S, et al.
Nat Commun
. 2022 Feb;
13(1):1030.
PMID: 35210413
Coinfections with pathogenic microbes continually confront cervical mucosa, yet their implications in pathogenesis remain unclear. Lack of in-vitro models recapitulating cervical epithelium has been a bottleneck to study coinfections. Using...
8.
Gurumurthy R, Kumar N, Chumduri C
STAR Protoc
. 2021 Nov;
2(4):100970.
PMID: 34841281
Single-cell RNA sequencing (scRNA-seq) is a powerful tool for enumerating the gene expression dynamics at single-cell resolution. Various organs comprising distinct cellular composition and architecture require unique approaches for highly...
9.
Gurumurthy R, Kumar N, Chumduri C
STAR Protoc
. 2021 Nov;
2(4):100969.
PMID: 34841280
Visualizing precise spatial patterns of an organ-wide gene and protein expression among diverse cell types can provide critical insights into the fundamental processes underlying normal tissue homeostasis and disease development....
10.
Chumduri C, Turco M
J Mol Med (Berl)
. 2021 Feb;
99(4):531-553.
PMID: 33580825
Healthy functioning of the female reproductive tract (FRT) depends on balanced and dynamic regulation by hormones during the menstrual cycle, pregnancy and childbirth. The mucosal epithelial lining of different regions...