Volker Brinkmann
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Explore the profile of Volker Brinkmann including associated specialties, affiliations and a list of published articles.
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170
Citations
22287
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Recent Articles
1.
Marsman G, Zheng X, cerina D, Lacey K, Liu M, Humme D, et al.
Cell Rep
. 2024 Nov;
43(11):114969.
PMID: 39546397
The antimicrobial activity of histones was discovered in the 1940s, but their mechanism of action is not fully known. Here we show that methicillin-resistant Staphylococcus aureus (MRSA) is susceptible to...
2.
Herbert M, Goosmann C, Brinkmann V, Dimmler C, Cronan M
J Immunol
. 2024 Oct;
213(12):1893-1901.
PMID: 39465974
Eosinophils control many aspects of the vertebrate innate immune response. They contribute to homeostasis, inflammatory conditions and defense against pathogens. With the varied functions of eosinophils, they have been found...
3.
Arias-Rojas A, Arifah A, Angelidou G, Alshaar B, Schombel U, Forest E, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012462.
PMID: 39159259
Multiple peptide resistance factor (MprF) confers resistance to cationic antimicrobial peptides (AMPs) in several pathogens, thereby enabling evasion of the host immune response. The role of MprF in commensals remains,...
4.
Kumar N, Prakash P, Wentland C, Kurian S, Jethva G, Brinkmann V, et al.
Nat Commun
. 2024 Apr;
15(1):3064.
PMID: 38594232
The gastroesophageal squamocolumnar junction (GE-SCJ) is a critical tissue interface between the esophagus and stomach, with significant relevance in the pathophysiology of gastrointestinal diseases. Despite this, the molecular mechanisms underlying...
5.
Nieuwenhuizen N, Nouailles G, Sutherland J, Zyla J, Pasternack A, Heyckendorf J, et al.
mBio
. 2024 Feb;
15(3):e0340823.
PMID: 38376260
Importance: Tuberculosis remains the leading cause of death by a bacterial pathogen. The etiologic agent of tuberculosis, , can remain dormant in the infected host for years before causing disease....
6.
Arias-Rojas A, Frahm D, Hurwitz R, Brinkmann V, Iatsenko I
Proc Natl Acad Sci U S A
. 2023 Aug;
120(36):e2305649120.
PMID: 37639605
Resilience to short-term perturbations, like inflammation, is a fundamental feature of microbiota, yet the underlying mechanisms of microbiota resilience are incompletely understood. Here, we show that , a major commensal,...
7.
Buijze H, Brinkmann V, Hurwitz R, Dorhoi A, Kaufmann S, Pei G
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298652
Mouse guanylate-binding proteins (mGBPs) are recruited to various invasive pathogens, thereby conferring cell-autonomous immunity against these pathogens. However, whether and how human GBPs (hGBPs) target (Mtb) and (Lm) remains unclear....
8.
Hach T, Shakeri-Nejad K, Bigaud M, Dahlke F, de Micco M, Petricoul O, et al.
J Interferon Cytokine Res
. 2022 Dec;
43(6):246-256.
PMID: 36454249
Maladjusted immune responses to the coronavirus disease 2019 (COVID-19), for example, cytokine release syndrome, may result in immunopathology and acute respiratory distress syndrome. Sphingosine-1-phosphate (S1P), a bioactive lipid mediator, and...
9.
Tilley D, Abuabed U, Zimny Arndt U, Schmid M, Florian S, Jungblut P, et al.
Elife
. 2022 Oct;
11.
PMID: 36282064
Neutrophils are critical to host defence, executing diverse strategies to perform their antimicrobial and regulatory functions. One tactic is the production of neutrophil extracellular traps (NETs). In response to certain...
10.
Koster S, Gurumurthy R, Kumar N, Prakash P, Dhanraj J, Bayer S, et al.
Nat Commun
. 2022 Feb;
13(1):1030.
PMID: 35210413
Coinfections with pathogenic microbes continually confront cervical mucosa, yet their implications in pathogenesis remain unclear. Lack of in-vitro models recapitulating cervical epithelium has been a bottleneck to study coinfections. Using...