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Cindo O Nicholson

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Articles 9
Citations 740
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Recent Articles
1.
Lai W, Stumpo D, Wells M, Gruzdev A, Hicks S, Nicholson C, et al.
Mol Cell Biol . 2019 May; 39(13). PMID: 31036567
Tristetraprolin (TTP) is an anti-inflammatory protein that modulates the stability of certain cytokine/chemokine mRNAs. After initial high-affinity binding to AU-rich elements in 3' untranslated regions of target mRNAs, mediated through...
2.
Paul L, Carlin E, Jenkins M, Tan A, Barcellona C, Nicholson C, et al.
Clin Transl Immunology . 2017 Jan; 5(12):e117. PMID: 28090318
For decades, human infections with Zika virus (ZIKV), a mosquito-transmitted flavivirus, were sporadic, associated with mild disease, and went underreported since symptoms were similar to other acute febrile diseases. Recent...
3.
Nicholson C, Friedersdorf M, Bisogno L, Keene J
Methods . 2016 Nov; 118-119:16-23. PMID: 27840290
Post-transcriptional processes orchestrate gene expression through dynamic protein-RNA interactions. These interactions occur at specific sites determined by RNA sequence, secondary structure, or nucleotide modifications. Methods have been developed either to...
4.
Nicholson C, Friedersdorf M, Keene J
RNA . 2016 Oct; 23(1):32-46. PMID: 27742911
RNA-binding proteins (RBPs) and noncoding RNAs orchestrate post-transcriptional processes through the recognition of specific sites on targeted transcripts. Thus, understanding the connection between binding to specific sites and active regulation...
5.
Smola M, Christy T, Inoue K, Nicholson C, Friedersdorf M, Keene J, et al.
Proc Natl Acad Sci U S A . 2016 Sep; 113(37):10322-7. PMID: 27578869
The 18-kb Xist long noncoding RNA (lncRNA) is essential for X-chromosome inactivation during female eutherian mammalian development. Global structural architecture, cell-induced conformational changes, and protein-RNA interactions within Xist are poorly...
6.
Tomaras G, Ferrari G, Shen X, Alam S, Liao H, Pollara J, et al.
Proc Natl Acad Sci U S A . 2013 May; 110(22):9019-24. PMID: 23661056
Analysis of correlates of risk of infection in the RV144 HIV-1 vaccine efficacy trial demonstrated that plasma IgG against the HIV-1 envelope (Env) variable region 1 and 2 inversely correlated...
7.
Costin J, Zaitseva E, Kahle K, Nicholson C, Rowe D, Graham A, et al.
J Virol . 2012 Oct; 87(1):52-66. PMID: 23077306
There are no available vaccines for dengue, the most important mosquito-transmitted viral disease. Mechanistic studies with anti-dengue virus (DENV) human monoclonal antibodies (hMAbs) provide a rational approach to identify and...
8.
Nicholson C, Costin J, Rowe D, Lin L, Jenwitheesuk E, Samudrala R, et al.
Antiviral Res . 2010 Nov; 89(1):71-4. PMID: 21093488
Severe dengue virus (DENV) disease symptoms, including dengue hemorrhagic fever and dengue shock syndrome, have been correlated with the presence of pre-existing antibodies that enhance rather than neutralize infections in...
9.
Schieffelin J, Costin J, Nicholson C, Orgeron N, Fontaine K, Isern S, et al.
Virol J . 2010 Feb; 7:28. PMID: 20132551
Background: Antibodies produced in response to infection with any of the four serotypes of dengue virus generally provide homotypic immunity. However, prior infection or circulating maternal antibodies can also mediate...