Cierra N Sing
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Explore the profile of Cierra N Sing including associated specialties, affiliations and a list of published articles.
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11
Citations
229
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Recent Articles
1.
Sing C, Garcia E, Lipkin T, Huckaba T, Tsang C, Coughlin A, et al.
Nat Commun
. 2022 May;
13(1):2706.
PMID: 35577788
In yeast, actin cables are F-actin bundles that are essential for cell division through their function as tracks for cargo movement from mother to daughter cell. Actin cables also affect...
2.
Liao P, Yang E, Borgman T, Boldogh I, Sing C, Swayne T, et al.
Front Cell Dev Biol
. 2022 Mar;
10:852021.
PMID: 35281095
Lipid droplets (LDs) have emerged not just as storage sites for lipids but as central regulators of metabolism and organelle quality control. These critical functions are achieved, in part, at...
3.
Sing C, Yang E, Higuchi-Sanabria R, Pon L, Boldogh I, Swayne T
Methods Mol Biol
. 2021 Sep;
2364:81-100.
PMID: 34542849
Budding yeast, Saccharomyces cerevisiae, is an appealing model organism to study the organization and function of the actin cytoskeleton. With the advent of techniques to perform high-resolution, multidimensional analysis of...
4.
Sing C, Yang E, Swayne T, Higuchi-Sanabria R, Tsang C, Boldogh I, et al.
Methods Mol Biol
. 2021 Sep;
2364:53-80.
PMID: 34542848
Although budding yeast, Saccharomyces cerevisiae, is widely used as a model organism in biological research, studying cell biology in yeast was hindered due to its small size, rounded morphology, and...
5.
Garcia E, Liao P, Tan G, Vevea J, Sing C, Tsang C, et al.
Autophagy
. 2020 Oct;
17(9):2363-2383.
PMID: 33021864
Our previous studies reveal a mechanism for lipid droplet (LD)-mediated proteostasis in the endoplasmic reticulum (ER) whereby unfolded proteins that accumulate in the ER in response to lipid imbalance-induced ER...
6.
Higuchi-Sanabria R, Shen K, Kelet N, Frankino P, Durieux J, Bar-Ziv R, et al.
Sci Adv
. 2020 Jul;
6(26):eaaz9805.
PMID: 32637599
Recent work has highlighted the fact that lysosomes are a critical signaling hub of metabolic processes, providing fundamental building blocks crucial for anabolic functions. How lysosomal functions affect other cellular...
7.
Liao P, Higuchi-Sanabria R, Swayne T, Sing C, Pon L
Methods Cell Biol
. 2020 Mar;
155:519-544.
PMID: 32183975
Mitochondria are highly dynamic organelles that undergo directed movement and anchorage, which in turn are critical for calcium buffering and energy mobilization at specific regions within cells or at sites...
8.
Garcia E, de Jonge J, Liao P, Stivison E, Sing C, Higuchi-Sanabria R, et al.
Mol Biol Cell
. 2019 Oct;
30(24):2943-2952.
PMID: 31599702
Loss of mitochondrial DNA (mtDNA) results in loss of mitochondrial respiratory activity, checkpoint-regulated inhibition of cell cycle progression, defects in growth, and nuclear genome instability. However, after several generations, yeast...
9.
Chen X, Wang G, Zhang Y, Dayhoff-Brannigan M, Diny N, Zhao M, et al.
PLoS Genet
. 2018 Aug;
14(8):e1007592.
PMID: 30142151
Yeast WHI2 was originally identified in a genetic screen for regulators of cell cycle arrest and later suggested to function in general stress responses. However, the function of Whi2 is...
10.
Higuchi-Sanabria R, Charalel J, Viana M, Garcia E, Sing C, Koenigsberg A, et al.
Mol Biol Cell
. 2016 Jan;
27(5):776-87.
PMID: 26764088
Higher-functioning mitochondria that are more reduced and have less ROS are anchored in the yeast bud tip by the Dsl1-family protein Mmr1p. Here we report a role for mitochondrial fusion...