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Cian McCafferty

Explore the profile of Cian McCafferty including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 234
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Recent Articles
1.
Sieu L, Singla S, Liu J, Zheng X, Sharafeldin A, Chandrasekaran G, et al.
Cell Rep . 2024 Dec; 43(12):115012. PMID: 39643969
Patients with focal temporal lobe seizures often experience loss of consciousness associated with cortical slow waves, like those in deep sleep. Previous work in rat models suggests that decreased subcortical...
2.
Khan W, Chopra S, Zheng X, Liu S, Paszkowski P, Valcarce-Aspegren M, et al.
Exp Neurol . 2024 Aug; 381:114925. PMID: 39151596
Objectives: Absence seizures impair psychosocial function, yet their detailed neuronal basis remains unknown. Recent work in a rat model suggests that cortical arousal state changes prior to seizures and that...
3.
McCafferty C, Gruenbaum B, Tung R, Li J, Zheng X, Salvino P, et al.
Nat Commun . 2023 Jan; 14(1):117. PMID: 36627270
Absence seizures are brief episodes of impaired consciousness, behavioral arrest, and unresponsiveness, with yet-unknown neuronal mechanisms. Here we report that an awake female rat model recapitulates the behavioral, electroencephalographic, and...
4.
McCafferty C, Russo E, Striano P
Neurobiol Dis . 2022 Nov; 175:105935. PMID: 36442713
No abstract available.
5.
McCafferty C
EBioMedicine . 2022 Mar; 78:103924. PMID: 35339095
No abstract available.
6.
Gummadavelli A, Martin R, Goshay D, Sieu L, Xu J, Gruenbaum B, et al.
Epilepsia . 2021 Jul; 62(8):1960-1970. PMID: 34240747
Objective: Impairment in consciousness is a debilitating symptom during and after seizures; however, its mechanism remains unclear. Limbic seizures have been shown to spread to arousal circuitry to result in...
7.
Crunelli V, Lorincz M, McCafferty C, Lambert R, Leresche N, Di Giovanni G, et al.
Brain . 2020 May; 143(8):2341-2368. PMID: 32437558
Absence seizures in children and teenagers are generally considered relatively benign because of their non-convulsive nature and the large incidence of remittance in early adulthood. Recent studies, however, show that...
8.
McCafferty C, Connelly W, Celli R, Ngomba R, Nicoletti F, Crunelli V
CNS Neurosci Ther . 2018 Apr; 24(8):745-758. PMID: 29687641
No abstract available.
9.
McCafferty C, David F, Venzi M, Lorincz M, Delicata F, Atherton Z, et al.
Nat Neurosci . 2018 Apr; 21(5):744-756. PMID: 29662216
Behaviorally and pathologically relevant cortico-thalamo-cortical oscillations are driven by diverse interacting cell-intrinsic and synaptic processes. However, the mechanism that gives rise to the paroxysmal oscillations of absence seizures (ASs) remains...
10.
Feng L, Motelow J, Ma C, Biche W, McCafferty C, Smith N, et al.
J Neurosci . 2017 Oct; 37(47):11441-11454. PMID: 29066556
The thalamus plays diverse roles in cortical-subcortical brain activity patterns. Recent work suggests that focal temporal lobe seizures depress subcortical arousal systems and convert cortical activity into a pattern resembling...