Abhijeet Gummadavelli
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Explore the profile of Abhijeet Gummadavelli including associated specialties, affiliations and a list of published articles.
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Citations
356
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Recent Articles
1.
Doss D, Gummadavelli A, Johnson G, Makhoul G, Shless J, Bibro C, et al.
J Neurosurg
. 2025 Jan;
:1-10.
PMID: 39854724
Objective: Epilepsy is a common neurological disease affecting nearly 1% of the global population, and temporal lobe epilepsy (TLE) is the most common type. Patients experience recurrent seizures and chronic...
2.
Sieu L, Singla S, Liu J, Zheng X, Sharafeldin A, Chandrasekaran G, et al.
Cell Rep
. 2024 Dec;
43(12):115012.
PMID: 39643969
Patients with focal temporal lobe seizures often experience loss of consciousness associated with cortical slow waves, like those in deep sleep. Previous work in rat models suggests that decreased subcortical...
3.
Doss D, Johnson G, Makhoul G, Rashingkar R, Shless J, Bibro C, et al.
Epilepsia
. 2024 Jul;
65(9):2686-2699.
PMID: 39056406
Objective: Epilepsy is a common neurological disorder affecting 1% of the global population. Loss of consciousness in focal impaired awareness seizures (FIASs) and focal-to-bilateral tonic-clonic seizures (FBTCSs) can be devastating,...
4.
Doss D, Shless J, Bick S, Makhoul G, Negi A, Bibro C, et al.
Brain
. 2024 Jun;
147(9):3009-3017.
PMID: 38874456
Successful surgical treatment of drug-resistant epilepsy traditionally relies on the identification of seizure onset zones (SOZs). Connectome-based analyses of electrographic data from stereo electroencephalography (SEEG) may empower improved detection of...
5.
Johnson G, Doss D, Morgan V, Paulo D, Cai L, Shless J, et al.
Brain
. 2023 Feb;
146(7):2828-2845.
PMID: 36722219
Why are people with focal epilepsy not continuously having seizures? Previous neuronal signalling work has implicated gamma-aminobutyric acid balance as integral to seizure generation and termination, but is a high-level...
6.
Gummadavelli A, Englot D, Schwalb J, Wu C, Gonzalez-Martinez J, Niemat J, et al.
Neurosurgery
. 2022 Mar;
90(5):636-641.
PMID: 35271523
Neuromodulation has taken a foothold in the landscape of surgical treatment for medically refractory epilepsies and offers additional surgical treatment options for patients who are not candidates for resective/ablative surgery....
7.
Gummadavelli A, Martin R, Goshay D, Sieu L, Xu J, Gruenbaum B, et al.
Epilepsia
. 2021 Jul;
62(8):1960-1970.
PMID: 34240747
Objective: Impairment in consciousness is a debilitating symptom during and after seizures; however, its mechanism remains unclear. Limbic seizures have been shown to spread to arousal circuitry to result in...
8.
Zhao C, Feng L, Sieu L, Pok B, Gummadavelli A, Blumenfeld H
Epilepsia
. 2020 Nov;
61(12):e186-e191.
PMID: 33165921
Focal limbic seizures can cause loss of consciousness. Previous work suggests that hippocampal seizures can increase activity in the lateral septum (LS) and decrease cholinergic output from the basal forebrain...
9.
Xu J, Galardi M, Pok B, Patel K, Zhao C, Andrews J, et al.
J Neurosci
. 2020 Aug;
40(38):7343-7354.
PMID: 32826310
The postictal state following seizures is characterized by impaired consciousness and has a major negative impact on individuals with epilepsy. Previous work in disorders of consciousness including the postictal state...
10.
Gummadavelli A, Dinauer C, McGuone D, Vining E, Erson-Omay E, Omay S
J Clin Neurosci
. 2020 Apr;
78:420-422.
PMID: 32336638
Gigantism (early-onset acromegaly) is a rare pediatric disorder caused by a growth hormone (GH)-secreting pituitary adenoma. Approximately 50% patients of gigantism have a germline mutation, most commonly an inactivating mutation...