Chun Yin Jerry Lau
Overview
Explore the profile of Chun Yin Jerry Lau including associated specialties, affiliations and a list of published articles.
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12
Citations
75
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Recent Articles
1.
Benne N, Ter Braake D, Porenta D, Lau C, Mastrobattista E, Broere F
Adv Healthc Mater
. 2024 Jan;
13(12):e2304238.
PMID: 38295848
There is no curative treatment for chronic auto-inflammatory diseases including rheumatoid arthritis, and current treatments can induce off-target side effects due to systemic immune suppression. This work has previously shown...
2.
Liu M, Lau C, Cabello I, Garssen J, Willemsen L, Hennink W, et al.
Pharmaceuticals (Basel)
. 2023 Jun;
16(6).
PMID: 37375766
Our previous study demonstrated that a selected β-lactoglobulin-derived peptide (BLG-Pep) loaded in poly(lactic--glycolic acid) (PLGA) nanoparticles protected mice against cow's milk allergy development. However, the mechanism(s) responsible for the interaction...
3.
Uchida S, Lau C, Oba M, Miyata K
Adv Drug Deliv Rev
. 2023 Jun;
199:114972.
PMID: 37364611
Nanoparticle-based delivery systems have contributed to the recent clinical success of RNA therapeutics, including siRNA and mRNA. RNA delivery using polymers has several distinct properties, such as enabling RNA delivery...
4.
Lau C, Fontana F, Mandemaker L, Wezendonk D, Vermeer B, Bonvin A, et al.
Commun Chem
. 2023 Jan;
3(1):179.
PMID: 36703417
No abstract available.
5.
Lau C, Fontana F, Mandemaker L, Wezendonk D, Vermeer B, Bonvin A, et al.
Commun Chem
. 2023 Jan;
3(1):164.
PMID: 36703336
Self-assembling peptides are an exemplary class of supramolecular biomaterials of broad biomedical utility. Mechanistic studies on the peptide self-assembly demonstrated the importance of the oligomeric intermediates towards the properties of...
6.
Modulating albumin-mediated transport of peptide-drug conjugates for antigen-specific Treg induction
Lau C, Benne N, Lou B, Zharkova O, Ting H, Ter Braake D, et al.
J Control Release
. 2022 Jun;
348:938-950.
PMID: 35732251
The therapeutic potential of antigen-specific regulatory T cells (Treg) has been extensively explored, leading to the development of several tolerogenic vaccines. Dexamethasone-antigen conjugates represent a prominent class of tolerogenic vaccines...
7.
Lau C, Benne N, Lou B, Ter Braake D, Bosman E, van Kronenburg N, et al.
J Pharm Sci
. 2022 Feb;
111(4):1004-1011.
PMID: 35120963
Induction of antigen-specific immune tolerance has emerged as the next frontier in treating autoimmune disorders, including atherosclerosis and graft-vs-host reactions during transplantation. Nanostructures are under investigation as a platform for...
8.
Ter Braake D, Benne N, Lau C, Mastrobattista E, Broere F
Pharmaceutics
. 2021 Nov;
13(11).
PMID: 34834364
The current treatment of autoimmune and chronic inflammatory diseases entails systemic immune suppression, which is associated with increased susceptibility to infections. To restore immune tolerance and reduce systemic side effects,...
9.
Lou B, Lau C, Hennink W, Mastrobattista E
Methods Mol Biol
. 2021 Aug;
2355:275-286.
PMID: 34386965
Successful delivery of mRNA into the cytosol of professional antigen-presenting cells (APCs) poses one of the biggest challenges in developing effective mRNA vaccines to treat various cancers and viral infectious...
10.
Nijen Twilhaar M, Czentner L, Grabowska J, Affandi A, Lau C, Olesek K, et al.
Pharmaceutics
. 2020 Dec;
12(12).
PMID: 33255564
Despite promising progress in cancer vaccination, therapeutic effectiveness is often insufficient. Cancer vaccine effectiveness could be enhanced by targeting vaccine antigens to antigen-presenting cells, thereby increasing T-cell activation. CD169-expressing splenic...