Chun P Chow
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Explore the profile of Chun P Chow including associated specialties, affiliations and a list of published articles.
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8
Citations
74
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Recent Articles
1.
Palanki M, Cao J, Chow C, Dneprovskaia E, Mak C, McPherson A, et al.
Expert Opin Drug Discov
. 2013 Mar;
4(1):33-49.
PMID: 23480335
Background: The synthesis of novel benzotriazine heterocycles was developed independently around the same time by Bischler, Bamberger and Arndt. Over the years, different groups have reported the synthesis of benzotriazine...
2.
Noronha G, Cao J, Chow C, Dneprovskaia E, Fine R, Hood J, et al.
Curr Top Med Chem
. 2008 Aug;
8(10):905-21.
PMID: 18673174
Chronic myelogenous leukemia (CML) is a hematological stem cell disorder caused by increased and unregulated growth of myeloid cells in the bone marrow, and the accumulation of excessive white blood...
3.
Palanki M, Akiyama H, Campochiaro P, Cao J, Chow C, Dellamary L, et al.
J Med Chem
. 2008 Mar;
51(6):1546-59.
PMID: 18311895
Age-related macular degeneration (AMD) is one of the leading causes of loss of vision in the industrialized world. Attenuating the VEGF signal in the eye to treat AMD has been...
4.
Molina C, Chow C, Shea K
J Org Chem
. 2007 Aug;
72(18):6816-23.
PMID: 17676912
The type 2 intramolecular N-acylazo Diels-Alder reaction provides a regio- and stereoselective synthesis of bicyclic 1,2-diazine systems. A new method for the generation of N-acylazo dienophiles with tetra-n-butylammonium periodate is...
5.
Noronha G, Barrett K, Boccia A, Brodhag T, Cao J, Chow C, et al.
Bioorg Med Chem Lett
. 2006 Nov;
17(3):602-8.
PMID: 17113292
We describe the identification of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine (3), a potent, orally active Src inhibitor with desirable PK properties, demonstrated activity in human tumor cell lines and in animal models of...
6.
Chow C, Shea K
J Am Chem Soc
. 2005 Mar;
127(11):3678-9.
PMID: 15771485
The chiral ruthenium salen complex, 13b, functions as an efficient catalyst for the sequential oxidation and asymmetric Diels-Alder cycloaddition of hydroxamic acids and N-hydroxy formate esters. This result provides evidence...
7.
Sparks S, Chow C, Zhu L, Shea K
J Org Chem
. 2004 Apr;
69(9):3025-35.
PMID: 15104440
Heteroatom variants of the type 2 intramolecular Diels-Alder reaction provide an efficient method for the preparation of bridged bicyclic heterocycles. The type 2 variant of the intramolecular N-acylnitroso Diels-Alder reaction...
8.
Chow C, Shea K, Sparks S
Org Lett
. 2002 Aug;
4(16):2637-40.
PMID: 12153197
[reaction: see text] The type 2 intramolecular N-acylnitroso Diels-Alder reaction has been employed for the synthesis of substituted bridged bicyclic oxazinolactams. Upon oxidation of hydroxamic acid 6, a 3-benzylated oxazinolactam...