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» Authors » Chulbul M I Ahmed

Chulbul M I Ahmed

Explore the profile of Chulbul M I Ahmed including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 211
Followers 0
Related Specialties
Allergy & Immunology
Biochemistry
Neurology
Top 10 Co-Authors
Howard M Johnson
Lindsey D Jager
Rea Dabelic
S Mohammad Haider
Joseph Larkin 3rd
Ezra N Noon-Song
Prem S Subramaniam
Samuel David
Alex J Fulcher
David A Jans
Published In
J Immunol
J Virol
J Neuroimmunol
Front Immunol
FEBS Lett
Affiliations
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Recent Articles
1.
SOCS1 Mimetics and Antagonists: A Complementary Approach to Positive and Negative Regulation of Immune Function
Ahmed C, Larkin 3rd J, Johnson H
Front Immunol . 2015 May; 6:183. PMID: 25954276
Suppressors of cytokine signaling (SOCS) are inducible intracellular proteins that play essential regulatory roles in both immune and non-immune function. Of the eight known members, SOCS1 and SOCS3 in conjunction...
2.
The kinase inhibitory region of SOCS-1 is sufficient to inhibit T-helper 17 and other immune functions in experimental allergic encephalomyelitis
Jager L, Dabelic R, Waiboci L, Lau K, Haider M, Ahmed C, et al.
J Neuroimmunol . 2010 Dec; 232(1-2):108-18. PMID: 21131060
Suppressors of cytokine signaling (SOCS) negatively regulate the immune response, primarily by interfering with the JAK/STAT pathway. We have developed a small peptide corresponding to the kinase inhibitory region (KIR)...
3.
Enhancement of antiviral immunity by small molecule antagonist of suppressor of cytokine signaling
Ahmed C, Dabelic R, Martin J, Jager L, Haider S, Johnson H
J Immunol . 2010 Jun; 185(2):1103-13. PMID: 20543109
Suppressors of cytokine signaling (SOCSs) are negative regulators of both innate and adaptive immunity via inhibition of signaling by cytokines such as type I and type II IFNs. We have...
4.
HSV-1-induced SOCS-1 expression in keratinocytes: use of a SOCS-1 antagonist to block a novel mechanism of viral immune evasion
Frey K, Ahmed C, Dabelic R, Jager L, Noon-Song E, Haider S, et al.
J Immunol . 2009 Jun; 183(2):1253-62. PMID: 19542368
Keratinocytes are important for the acute phase of HSV-1 infection and subsequent persistence in sensory nervous tissue. In this study, we showed that keratinocytes (HEL-30) were refractory to IFN-gamma induction...
5.
Interferon gamma is recognised by importin alpha/beta: enhanced nuclear localising and transactivation activities of an interferon gamma mimetic
Fulcher A, Ahmed C, Noon-Song E, Kwan R, Subramaniam P, Johnson H, et al.
FEBS Lett . 2008 Apr; 582(11):1569-74. PMID: 18405666
Interferon (IFN) gamma's ability to localise in the nucleus and function in gene activation has been known for some time, although the role of the conventional nuclear transporting importin molecules...
6.
IFN-gamma and its receptor subunit IFNGR1 are recruited to the IFN-gamma-activated sequence element at the promoter site of IFN-gamma-activated genes: evidence of transactivational activity in IFNGR1
Ahmed C, Johnson H
J Immunol . 2006 Jun; 177(1):315-21. PMID: 16785527
We have shown previously that IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway....
7.
Peptide mimetics of gamma interferon possess antiviral properties against vaccinia virus and other viruses in the presence of poxvirus B8R protein
Ahmed C, Burkhart M, Subramaniam P, Mujtaba M, Johnson H
J Virol . 2005 Apr; 79(9):5632-9. PMID: 15827178
We have developed peptide mimetics of gamma interferon (IFN-gamma) that play a direct role in the activation and nuclear translocation of STAT1alpha transcription factor. These mimetics do not act through...