Christy A Comeaux
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Explore the profile of Christy A Comeaux including associated specialties, affiliations and a list of published articles.
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14
Citations
259
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Recent Articles
1.
van Heesbeen R, Bastian A, Omoruyi E, Rosen J, Comeaux C, Callendret B, et al.
Vaccine
. 2024 Sep;
42(26):126273.
PMID: 39276619
Background: Respiratory syncytial virus (RSV) can cause severe illness in older adults. A combination vaccine containing Ad26.RSV.preF and purified recombinant RSV preF protein has previously demonstrated efficacy and tolerability in...
2.
Eto T, Okubo Y, Momose A, Tamura H, Zheng R, Callendret B, et al.
Influenza Other Respir Viruses
. 2024 Jun;
18(6):e13336.
PMID: 38880785
Background: Respiratory syncytial virus (RSV) is increasingly recognized as a significant cause of lower respiratory tract disease (LRTD) in older adults. The Ad26.RSV.preF/RSV preF protein vaccine demonstrated protective efficacy against...
3.
Falsey A, Hosman T, Bastian A, Vandenberghe S, Chan E, Douoguih M, et al.
Lancet Infect Dis
. 2024 May;
24(9):1015-1024.
PMID: 38801826
Background: Ad26.RSV.preF-RSV preF protein showed 80·0% vaccine efficacy against respiratory syncytial virus (RSV) lower respiratory tract disease (LRTD) in older adults during one RSV season. No RSV vaccines have shown...
4.
Widagdo W, Bastian A, Jastorff A, Scheys I, De Paepe E, Comeaux C, et al.
J Infect Dis
. 2023 Dec;
230(2):e374-e383.
PMID: 38134393
Background: Since influenza and respiratory syncytial virus (RSV) carry significant burden in older adults with overlapping seasonality, vaccines for both pathogens would ideally be coadministered in this population. Here we...
5.
Bartsch Y, Cizmeci D, Yuan D, Mehta N, Tolboom J, De Paepe E, et al.
J Virol
. 2023 Oct;
97(11):e0077123.
PMID: 37902399
Respiratory syncytial virus (RSV) can cause serious illness in older adults (i.e., those aged ≥60 years). Because options for RSV prophylaxis and treatment are limited, the prevention of RSV-mediated illness...
6.
Comeaux C, Bart S, Bastian A, Klyashtornyy V, De Paepe E, Omoruyi E, et al.
J Infect Dis
. 2023 Jul;
229(1):19-29.
PMID: 37433021
Background: Ad26.RSV.preF is an adenovirus serotype 26 vector-based respiratory syncytial virus (RSV) vaccine encoding a prefusion conformation-stabilized RSV fusion protein (preF) that demonstrated robust humoral and cellular immunogenicity and showed...
7.
Falsey A, Williams K, Gymnopoulou E, Bart S, Ervin J, Bastian A, et al.
N Engl J Med
. 2023 Feb;
388(7):609-620.
PMID: 36791161
Background: Respiratory syncytial virus (RSV) can cause serious lower respiratory tract disease in older adults, but no licensed RSV vaccine currently exists. An adenovirus serotype 26 RSV vector encoding a...
8.
Comeaux C, Coleman B, Bei A, Whitehurst N, Duraisingh M
Mol Microbiol
. 2011 Feb;
80(2):378-90.
PMID: 21320181
The Plasmodium RhopH complex is a high molecular weight antigenic complex consisting of three subunits - RhopH1/clag, RhopH2 and RhopH3 - located in the rhoptry secretory organelles of the invasive...
9.
Artavanis-Tsakonas K, Weihofen W, Antos J, Coleman B, Comeaux C, Duraisingh M, et al.
J Biol Chem
. 2010 Jan;
285(9):6857-66.
PMID: 20042598
Like their human hosts, Plasmodium falciparum parasites rely on the ubiquitin-proteasome system for survival. We previously identified PfUCHL3, a deubiquitinating enzyme, and here we characterize its activity and changes in...
10.
Militello K, Refour P, Comeaux C, Duraisingh M
Mol Biochem Parasitol
. 2007 Dec;
157(2):117-26.
PMID: 18053590
The complex life cycles of many protozoan parasites require the ability to respond to environmental and developmental cues through regulated gene expression. Traditionally, parasitologists have investigated these mechanisms by identifying...