Christos Kontos
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Explore the profile of Christos Kontos including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
111
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0
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Recent Articles
1.
El Bounkari O, Zan C, Yang B, Ebert S, Wagner J, Bugar E, et al.
Nat Commun
. 2025 Mar;
16(1):2297.
PMID: 40055309
Atherosclerosis is the underlying cause of myocardial infarction and ischemic stroke. It is a lipid-triggered and cytokine/chemokine-driven arterial inflammatory condition. We identify D-dopachrome tautomerase/macrophage migration-inhibitory factor-2 (MIF-2), a paralog of...
2.
Kontos C, Panagiotakopoulos T, Kameas A
Sensors (Basel)
. 2024 Oct;
24(19).
PMID: 39409311
Population growth and environmental burden have turned the efforts of cities globally toward smarter and greener mobility. Cooperative and Connected Automated Mobility (CCAM) serves as a concept with the power...
3.
Brandhofer M, Hoffmann A, Blanchet X, Siminkovitch E, Rohlfing A, El Bounkari O, et al.
Cell Mol Life Sci
. 2022 Sep;
79(10):512.
PMID: 36094626
To fulfil its orchestration of immune cell trafficking, a network of chemokines and receptors developed that capitalizes on specificity, redundancy, and functional selectivity. The discovery of heteromeric interactions in the...
4.
Kontos C, El Bounkari O, Krammer C, Sinitski D, Hille K, Zan C, et al.
Nat Commun
. 2020 Nov;
11(1):5981.
PMID: 33239628
Targeting a specific chemokine/receptor axis in atherosclerosis remains challenging. Soluble receptor-based strategies are not established for chemokine receptors due to their discontinuous architecture. Macrophage migration-inhibitory factor (MIF) is an atypical...
5.
Krammer C, Kontos C, Dewor M, Hille K, Volta B, El Bounkari O, et al.
Chembiochem
. 2020 Oct;
22(6):1012-1019.
PMID: 33125165
Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine and atypical chemokine with a key role in inflammatory diseases including atherosclerosis. Key atherogenic functions of MIF are mediated by noncognate...
6.
Sinitski D, Gruner K, Brandhofer M, Kontos C, Winkler P, Reinstadler A, et al.
J Biol Chem
. 2019 Dec;
295(3):850-867.
PMID: 31811089
Human macrophage migration-inhibitory factor (MIF) is an evolutionarily-conserved protein that has both extracellular immune-modulating and intracellular cell-regulatory functions. MIF plays a role in various diseases, including inflammatory diseases, atherosclerosis, autoimmunity,...
7.
Sinitski D, Kontos C, Krammer C, Asare Y, Kapurniotu A, Bernhagen J
Thromb Haemost
. 2019 Feb;
119(4):553-566.
PMID: 30716779
Chemokines orchestrate leukocyte recruitment in atherosclerosis and their blockade is a promising anti-atherosclerotic strategy, but few chemokine-based approaches have advanced into clinical trials, in part owing to the complexity and...
8.
Lacy M, Kontos C, Brandhofer M, Hille K, Groning S, Sinitski D, et al.
Sci Rep
. 2018 Mar;
8(1):5171.
PMID: 29581527
MIF is a chemokine-like cytokine that plays a role in the pathogenesis of inflammatory and cardiovascular disorders. It binds to the chemokine-receptors CXCR2/CXCR4 to trigger atherogenic leukocyte migration albeit lacking...
9.
Kontos C, Androutsou M, Vlamis-Gardikas A, Tselios T
Anal Biochem
. 2017 Sep;
538:71-73.
PMID: 28958915
The recovery of high molecular weight peptides from complex biological samples is a challenging task. Herein, a reliable, cost effective and rapid methodology was developed for the recovery and quantification...
10.
Kolnagou A, Michaelides Y, Kontos C, Kyriacou K, Kontoghiorghes G
Hemoglobin
. 2008 Feb;
32(1-2):17-28.
PMID: 18274979
Cardiac damage caused by iron overload toxicity is the main cause of death in thalassemia patients. Biopsy samples of poorly chelated thalassemia patients who suffered congestive cardiac failure (CCF) show...