Christopher T Workman
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Explore the profile of Christopher T Workman including associated specialties, affiliations and a list of published articles.
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77
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2433
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Recent Articles
1.
Kastberg L, Jacobsen I, Ozdemir E, Workman C, Jensen M, Forster J
FEMS Yeast Res
. 2025 Feb;
25.
PMID: 39971732
Yeast is a widely utilized chassis for heterologous protein production, with Komagataella phaffii well-established as a prominent nonconventional yeast in this field. Despite its widespread recognition, there remains considerable potential...
2.
Jian J, Wang Z, Chen C, Workman C, Fang X, Ostenfeld Larsen T, et al.
Microbiol Spectr
. 2024 Jun;
12(8):e0414823.
PMID: 38940543
Importance: The genus , characterized by its heterotrophic nature and pathogenicity, serves as an exemplary model for investigating pathobiology. The limited understanding of the protothecosis infectious disease is attributed to...
3.
Kastberg L, Petrov M, Strucko T, Jensen M, Workman C
ACS Synth Biol
. 2024 Feb;
13(3):714-720.
PMID: 38381624
Promoters are crucial elements for engineering microbial production strains used in bioprocesses. For the increasingly popular chassis (formerly ), a limited number of well-characterized promoters constrain the data-driven engineering of...
4.
Jian J, Wu Z, Silva-Nunez A, Li X, Zheng X, Luo B, et al.
Sci Total Environ
. 2023 Oct;
908:168042.
PMID: 37898203
Prymnesium parvum is a toxin-producing haptophyte that causes harmful algal blooms worldwide, which are often associated with massive fish-kills and subsequent economic losses. In here, we present nuclear and plastid...
5.
Kastberg L, Ard R, Jensen M, Workman C
Front Fungal Biol
. 2023 Sep;
3:827704.
PMID: 37746199
Production of heterologous proteins, especially biopharmaceuticals and industrial enzymes, in living cell factories consumes cellular resources. Such resources are reallocated from normal cellular processes toward production of the heterologous protein...
6.
Weith M, Grossbach J, Clement-Ziza M, Gillet L, Rodriguez-Lopez M, Marguerat S, et al.
Mol Syst Biol
. 2023 Jul;
19(8):e11493.
PMID: 37485750
The complexity of many cellular and organismal traits results from the integration of genetic and environmental factors via molecular networks. Network structure and effect propagation are best understood at the...
7.
Hartmann F, Weiss T, Kastberg L, Workman C, Seibold G
Front Microbiol
. 2023 Jun;
14:1187228.
PMID: 37389345
Genetically encoded fluorescent biosensors have emerged as a powerful tool to support phenotypic screenings of microbes. Optical analyses of fluorescent sensor signals from colonies grown on solid media can be...
8.
Moharrek F, Ingerslev L, Altintas A, Lundell L, Hansen A, Small L, et al.
Epigenomics
. 2022 Nov;
14(21):1305-1324.
PMID: 36420698
To perform a comparative epigenomic analysis of DNA methylation in spermatozoa from humans, mice, rats and mini-pigs. Genome-wide DNA methylation analysis was used to compare the methylation profiles of orthologous...
9.
Madsen C, Hein J, Workman C
PLoS Comput Biol
. 2022 Jun;
18(6):e1009414.
PMID: 35731801
Gene expression is controlled by pathways of regulatory factors often involving the activity of protein kinases on transcription factor proteins. Despite this well established mechanism, the number of well described...
10.
Rao W, Kalogeropoulos K, Allentoft M, Gopalakrishnan S, Zhao W, Workman C, et al.
Gigascience
. 2022 Apr;
11.
PMID: 35365832
Snake venoms represent a danger to human health, but also a gold mine of bioactive proteins that can be harnessed for drug discovery purposes. The evolution of snakes and their...