Ali Altintas
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Explore the profile of Ali Altintas including associated specialties, affiliations and a list of published articles.
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27
Citations
465
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Recent Articles
1.
Pinto A, Haytural H, Loss C, Loss C, Alvarez C, Ertas A, et al.
bioRxiv
. 2025 Feb;
PMID: 39896474
Muscle secretes factors during exercise that enhance cognition. Myokine Cathepsin B (Ctsb) is linked to memory function, but its role in neurodegenerative disease is unclear. Here we show that AAV-vector-mediated...
2.
Sanchez C, Colson C, Gautier N, Noser P, Salvi J, Villet M, et al.
Brain Behav Immun
. 2024 Feb;
117:330-346.
PMID: 38309640
Nutrient composition in obesogenic diets may influence the severity of disorders associated with obesity such as insulin-resistance and chronic inflammation. Here we hypothesized that obesogenic diets rich in fat and...
3.
Moharrek F, Ingerslev L, Altintas A, Lundell L, Hansen A, Small L, et al.
Epigenomics
. 2022 Nov;
14(21):1305-1324.
PMID: 36420698
To perform a comparative epigenomic analysis of DNA methylation in spermatozoa from humans, mice, rats and mini-pigs. Genome-wide DNA methylation analysis was used to compare the methylation profiles of orthologous...
4.
Pillon N, Sardon Puig L, Altintas A, Kamble P, Casani-Galdon S, Gabriel B, et al.
Life Sci Alliance
. 2022 Oct;
6(1).
PMID: 36302651
Obesity and elevated circulating lipids may impair metabolism by disrupting the molecular circadian clock. We tested the hypothesis that lipid overload may interact with the circadian clock and alter the...
5.
McIlvenna L, Altintas A, Patten R, McAinch A, Rodgers R, Stepto N, et al.
J Physiol
. 2022 Jun;
600(14):3313-3330.
PMID: 35760527
Polycystic ovary syndrome (PCOS) is characterised by a hormonal imbalance affecting the reproductive and metabolic health of reproductive-aged women. Exercise is recommended as a first-line therapy for women with PCOS...
6.
Isidor M, Dong W, Servin-Uribe R, Villarroel J, Altintas A, Ayala-Sumuano J, et al.
Int J Obes (Lond)
. 2021 Nov;
46(3):535-543.
PMID: 34799672
Background: In obesity, adipose tissue dysfunction resulting from excessive fat accumulation leads to systemic insulin resistance (IR), the underlying alteration of Type 2 Diabetes. The specific pathways dysregulated in dysfunctional...
7.
Non-cell autonomous mechanisms control mitochondrial gene dysregulation in polycystic ovary syndrome
Moreno-Asso A, Altintas A, McIlvenna L, Patten R, Botella J, McAinch A, et al.
J Mol Endocrinol
. 2021 Nov;
68(1):63-76.
PMID: 34752415
Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with insulin resistance and impaired energy metabolism in skeletal muscle, the aetiology of which is currently unclear. Here, we mapped...
8.
Gabriel B, Altintas A, Smith J, Sardon-Puig L, Zhang X, Basse A, et al.
Sci Adv
. 2021 Oct;
7(43):eabi9654.
PMID: 34669477
Circadian rhythms are generated by an autoregulatory feedback loop of transcriptional activators and repressors. Circadian rhythm disruption contributes to type 2 diabetes (T2D) pathogenesis. We elucidated whether altered circadian rhythmicity...
9.
Altintas A, Liu J, Fabre O, Chuang T, Wang Y, Sakurai R, et al.
FASEB J
. 2021 Jun;
35(7):e21702.
PMID: 34153130
Perinatal smoke/nicotine exposure alters lung development and causes asthma in exposed offspring, transmitted transgenerationally. The mechanism underlying the transgenerational inheritance of perinatal smoke/nicotine-induced asthma remains unknown, but germline epigenetic modulations...
10.
Nampt controls skeletal muscle development by maintaining Ca homeostasis and mitochondrial integrity
Basse A, Agerholm M, Farup J, Dalbram E, Nielsen J, Ortenblad N, et al.
Mol Metab
. 2021 Jun;
53:101271.
PMID: 34119711
Objective: NAD is a co-factor and substrate for enzymes maintaining energy homeostasis. Nicotinamide phosphoribosyltransferase (NAMPT) controls NAD synthesis, and in skeletal muscle, NAD is essential for muscle integrity. However, the...