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Christopher S Sullivan

Explore the profile of Christopher S Sullivan including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 3134
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Recent Articles
1.
Szymanik K, Hancks D, Sullivan C
bioRxiv . 2024 Aug; PMID: 39211142
Proper recognition of viral pathogens is an essential part of the innate immune response. A common viral replicative intermediate and chemical signal that cells use to identify pathogens is the...
2.
Parthasarathy S, Saenjamsai P, Hao H, Ferkul A, Pfannenstiel J, Suder E, et al.
bioRxiv . 2024 May; PMID: 38712082
PARP14 is a 203 kDa multi-domain protein that is primarily known as an ADP-ribosyltransferase, and is involved in a variety of cellular functions including DNA damage, microglial activation, inflammation, and...
3.
Cao P, Fleming D, Moustafa D, Dolan S, Szymanik K, Redman W, et al.
Nature . 2023 May; 618(7964):358-364. PMID: 37225987
The ability to switch between different lifestyles allows bacterial pathogens to thrive in diverse ecological niches. However, a molecular understanding of their lifestyle changes within the human host is lacking....
4.
Blois S, Goetz B, Bull J, Sullivan C
PLoS Comput Biol . 2022 Nov; 18(11):e1010131. PMID: 36413582
The concept of a nucleic acid barcode applied to pathogen genomes is easy to grasp and the many possible uses are straightforward. But implementation may not be easy, especially when...
5.
Yang R, Lee E, Kim J, Choi J, Kolitz E, Chen Y, et al.
PLoS Pathog . 2021 May; 17(5):e1009582. PMID: 33999949
Circular RNAs (circRNAs) are a conserved class of RNAs with diverse functions, including serving as messenger RNAs that are translated into peptides. Here we describe circular RNAs generated by human...
6.
Choi J, Sullivan C
PLoS Pathog . 2021 Jan; 17(1):e1009145. PMID: 33444401
No abstract available.
7.
Choi J, Burke J, Szymanik K, Nepal U, Battenhouse A, Lau J, et al.
Genes Dev . 2020 Nov; 34(23-24):1697-1712. PMID: 33184222
Deciphering the mechanisms that regulate the sensitivity of pathogen recognition receptors is imperative to understanding infection and inflammation. Here we demonstrate that the RNA triphosphatase dual-specificity phosphatase 11 (DUSP11) acts...
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Ragan K, Bhadra S, Choi J, Towers D, Sullivan C, Ellington A
medRxiv . 2020 Aug; PMID: 32793925
Since the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, there have been demands on the testing infrastructure that have strained testing capacity. As a simplification of...
10.
Grunewald M, Chen Y, Kuny C, Maejima T, Lease R, Ferraris D, et al.
PLoS Pathog . 2019 May; 15(5):e1007756. PMID: 31095648
ADP-ribosylation is a ubiquitous post-translational addition of either monomers or polymers of ADP-ribose to target proteins by ADP-ribosyltransferases, usually by interferon-inducible diphtheria toxin-like enzymes known as PARPs. While several PARPs...