Christopher S Lunde
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Explore the profile of Christopher S Lunde including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
198
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Recent Articles
1.
Cummings J, Lunde C, Alley M, Slayden R
PLoS Negl Trop Dis
. 2023 Nov;
17(11):e0011795.
PMID: 38011278
Burkholderia pseudomallei is the causative agent of melioidosis, which is increasingly being reported worldwide. Mortality rates as high as 40% have been reported based on clinical patient outcomes in the...
2.
Ehrens A, Lunde C, Jacobs R, Struever D, Koschel M, Frohberger S, et al.
PLoS Negl Trop Dis
. 2020 Jan;
14(1):e0007957.
PMID: 31986143
The elimination of filarial diseases such as onchocerciasis and lymphatic filariasis is hampered by the lack of a macrofilaricidal-adult worm killing-drug. In the present study, we tested the in vivo...
3.
Akama T, Freund Y, Berry P, Carter D, Easom E, Jarnagin K, et al.
ACS Infect Dis
. 2019 Dec;
6(2):173-179.
PMID: 31876154
A series of benzimidazole-benzoxaborole hybrid molecules linked via an amide linker are described that exhibit good activity against , a filarial nematode responsible for the disease onchocerciasis, also known as...
4.
Carter D, Jacobs R, Freund Y, Berry P, Akama T, Easom E, et al.
ACS Infect Dis
. 2019 Dec;
6(2):180-185.
PMID: 31876143
The optimization of a series of benzimidazole-benzoxaborole hybrid molecules linked via a ketone that exhibit good activity against , a filarial nematode responsible for the disease onchocerciasis, also known as...
5.
Lunde C, Stebbins E, Jumani R, Hasan M, Miller P, Barlow J, et al.
Nat Commun
. 2019 Jun;
10(1):2816.
PMID: 31249291
Cryptosporidiosis is a leading cause of life-threatening diarrhea in young children and causes chronic diarrhea in AIDS patients, but the only approved treatment is ineffective in malnourished children and immunocompromised...
6.
Jacobs R, Lunde C, Freund Y, Hernandez V, Li X, Xia Y, et al.
J Med Chem
. 2019 Feb;
62(5):2521-2540.
PMID: 30730745
A series of pleuromutilins modified by introduction of a boron-containing heterocycle on C(14) of the polycyclic core are described. These analogs were found to be potent anti- Wolbachia antibiotics and,...
7.
Song Y, Lunde C, Benton B, Wilkinson B
Microb Drug Resist
. 2013 Apr;
19(4):247-55.
PMID: 23551248
Telavancin is a novel semisynthetic lipoglycopeptide derivative of vancomycin with a dual mode of action. This study sought to understand the mechanisms of decreased telavancin susceptibility in a laboratory-derived Staphlococcus...
8.
Wang T, Sessions A, Lunde C, Rouhani S, Glaeser R, Duan Y, et al.
Structure
. 2013 Feb;
21(2):290-7.
PMID: 23394942
Despite extensive investigation, the precise mechanism controlling the opening of the cytoplasmic proton uptake pathway in bacteriorhodopsin (bR) has remained a mystery. From an analysis of the X-ray structure of...
9.
Krause K, Blais J, Lewis S, Lunde C, Barriere S, Friedland H, et al.
Diagn Microbiol Infect Dis
. 2012 Oct;
74(4):429-31.
PMID: 23083812
In phase 3 studies of the efficacy of telavancin for the treatment of hospital-acquired pneumonia, 704 Gram-positive and 627 Gram-negative aerobic bacterial pathogens were obtained at baseline from 1503 patients....
10.
Song Y, Lunde C, Benton B, Wilkinson B
Antimicrob Agents Chemother
. 2012 Mar;
56(6):3157-64.
PMID: 22411615
Telavancin is a novel semisynthetic lipoglycopeptide derivative of vancomycin with a decylaminoethyl side chain that is active against Gram-positive bacteria, including Staphylococcus aureus strains resistant to methicillin or vancomycin. A...