Robert M Glaeser
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Explore the profile of Robert M Glaeser including associated specialties, affiliations and a list of published articles.
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78
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1435
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Recent Articles
1.
Glaeser R
Ultramicroscopy
. 2025 Mar;
271:114118.
PMID: 40023013
Biological molecules are easily damaged by high-energy electrons, thus limiting the exposures that can be used to image such specimens by electron microscopy. It is argued here that many-electron, volume-plasmon...
2.
Remis J, Petrov P, Zhang J, Axelrod J, Cheng H, Sandhaus S, et al.
J Struct Biol
. 2024 Nov;
216(4):108150.
PMID: 39536845
Apoferritin (apoF) is commonly used as a test specimen in single-particle electron cryo-microscopy (cryo-EM), since it consistently produces density maps that go to 3 Å resolution or higher. When we...
3.
Remis J, Petrov P, Zhang J, Axelrod J, Cheng H, Sandhaus S, et al.
bioRxiv
. 2024 Aug;
PMID: 39149370
Apoferritin (apoF) is commonly used as a test specimen in single-particle electron cryo-microscopy (cryo-EM), since it consistently produces density maps that go to 3 Å resolution or higher. When we...
4.
Axelrod J, Zhang J, Petrov P, Glaeser R, Muller H
Curr Opin Struct Biol
. 2024 Mar;
86:102805.
PMID: 38531188
Although defocus can be used to generate partial phase contrast in transmission electron microscope images, cryo-electron microscopy (cryo-EM) can be further improved by the development of phase plates which increase...
5.
Axelrod J, Zhang J, Petrov P, Glaeser R, Mller H
ArXiv
. 2024 Feb;
PMID: 38344223
Although defocus can be used to generate partial phase contrast in transmission electron microscope images, cryo-electron microscopy (cryo-EM) can be further improved by the development of phase plates which increase...
6.
Han B, Avila-Sakar A, Remis J, Glaeser R
Curr Opin Struct Biol
. 2023 Jul;
81:102646.
PMID: 37392555
Recognizing that interaction with the air-water interface (AWI) is a major challenge for cryo-EM, we first review current approaches designed to avoid it. Of these, immobilizing particles on affinity grids...
7.
Axelrod J, Petrov P, Zhang J, Remis J, Buijsse B, Glaeser R, et al.
Ultramicroscopy
. 2023 Apr;
249:113730.
PMID: 37011498
We identify thermal magnetic field fluctuations, caused by thermal electron motion ("Johnson noise") in electrically conductive materials, as a potential resolution limit in transmission electron microscopy with a phase plate....
8.
Axelrod J, Petrov P, Zhang J, Remis J, Buijsse B, Glaeser R, et al.
bioRxiv
. 2023 Feb;
PMID: 36824829
We identify thermal magnetic field fluctuations, caused by thermal electron motion ("Johnson noise") in electrically conductive materials, as a potential resolution limit in transmission electron microscopy with a phase plate....
9.
Han B, Armstrong M, Fletcher D, Glaeser R
Front Mol Biosci
. 2022 May;
9:864829.
PMID: 35573724
While many aspects of single-particle electron cryo-microscopy (cryo-EM) of biological macromolecules have reached a sophisticated level of development, this is not yet the case when it comes to preparing thin...
10.
Petrov P, Muller H, Glaeser R
J Struct Biol
. 2021 Dec;
214(1):107827.
PMID: 34915129
In principle, electron cryo-tomography (cryo-ET) of thin portions of cells provides high-resolution images of the three-dimensional spatial arrangement of all members of the proteome. In practice, however, radiation damage creates...