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Christopher S Lepsy

Explore the profile of Christopher S Lepsy including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Wang M, Kussrow A, Fernandez Ocana M, Chabot J, Lepsy C, Bornhop D, et al.
Br J Pharmacol . 2016 Oct; 174(1):70-81. PMID: 27760281
Background And Purpose: A monoclonal antibody (PF-00547659) against mucosal addressin cell adhesion molecule (MAdCAM), expressed as both soluble (sMAdCAM) and trans-membrane (mMAdCAM) target forms, showed over 30-fold difference in antibody-target...
2.
Chang C, Duignan D, Johnson K, Lee P, Cowan G, Gifford E, et al.
J Pharm Sci . 2009 Jan; 98(8):2857-67. PMID: 19116953
As the cost of discovering and developing new pharmaceutically relevant compounds continues to rise, it is increasingly important to select the right molecules to prosecute very early in drug discovery....
3.
Stoner C, Gifford E, Stankovic C, Lepsy C, Brodfuehrer J, Prasad J, et al.
J Pharm Sci . 2004 Apr; 93(5):1131-41. PMID: 15067690
The pharmaceutical industry has large investments in compound library enrichment, high throughput biological screening, and biopharmaceutical (ADME) screening. As the number of compounds submitted for in vitro ADME screens increases,...
4.
Lepsy C, Guttendorf R, Kugler A, Smith D
Antimicrob Agents Chemother . 2003 Jan; 47(2):689-96. PMID: 12543679
Cefdinir (Omnicef; Abbott Laboratories) is a cephalosporin antibiotic primarily eliminated by the kidney. Nonlinear renal elimination of cefdinir has been previously reported. Cefdinir renal transport mechanisms were studied in the...