Christopher R Gignoux
Overview
Explore the profile of Christopher R Gignoux including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
113
Citations
5331
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Slack S, Esquinca E, Arehart C, Boorgula M, Szczesny B, Romero A, et al.
medRxiv
. 2025 Feb;
PMID: 39974046
Background: Genetic control of gene expression in asthma-related tissues is not well-characterized, particularly for African-ancestry populations, limiting advancement in our understanding of the increased prevalence and severity of asthma in...
2.
Liu H, Abedini A, Ha E, Ma Z, Sheng X, Dumoulin B, et al.
Science
. 2025 Feb;
387(6734):eadp4753.
PMID: 39913582
Kidney dysfunction is a major cause of mortality, but its genetic architecture remains elusive. In this study, we conducted a multiancestry genome-wide association study in 2.2 million individuals and identified...
3.
Stoneman H, Price A, Trout N, Lamont R, Tifour S, Pozdeyev N, et al.
Am J Hum Genet
. 2025 Jan;
112(2):235-253.
PMID: 39824191
Genetic summary data are broadly accessible and highly useful, including for risk prediction, causal inference, fine mapping, and incorporation of external controls. However, collapsing individual-level data into summary data, such...
4.
White S, Jamil T, Bell C, Fishbein L, Haugen B, Gignoux C, et al.
medRxiv
. 2024 Dec;
PMID: 39677421
Importance: A subset of thyroid cancers develops in a setting of a known hereditary cancer-associated syndrome. Understanding the population prevalence of thyroid cancer-associated syndromes is important to guide germline genetic...
5.
Pividori M, Sadeeq S, Krishnan A, Stranger B, Gignoux C
bioRxiv
. 2024 Nov;
PMID: 39605717
The growing availability of genome-wide association studies (GWAS) and large-scale biobanks provides an unprecedented opportunity to explore the genetic basis of complex traits and diseases. However, with this vast amount...
6.
Stoneman H, Price A, Gignoux C, Hendricks A
bioRxiv
. 2024 Nov;
PMID: 39554201
Methods involving summary statistics in genetics can be quite powerful but can be limited in utility. For instance, many post-hoc analyses of disease studies require case and control allele frequencies...
7.
Cataldo-Ramirez C, Lin M, Mcmahon A, Gignoux C, Weaver T, Henn B
bioRxiv
. 2024 Nov;
PMID: 39553939
Genome-wide association studies (GWAS) and polygenic score (PGS) development are typically constrained by the data available in biobank repositories in which European cohorts are vastly overrepresented. Here, we increase the...
8.
Liu S, Zhu J, Zhong H, Wu C, Xue H, Darst B, et al.
Diabetologia
. 2024 Sep;
67(12):2754-2770.
PMID: 39349773
Aims/hypothesis: Several studies have reported associations between specific proteins and type 2 diabetes risk in European populations. To better understand the role played by proteins in type 2 diabetes aetiology...
9.
Simon S, Lin M, Trinkley K, Aleong R, Rafaels N, Crooks K, et al.
PLoS One
. 2024 Jun;
19(6):e0303261.
PMID: 38885227
Drug-induced QT prolongation (diLQTS), and subsequent risk of torsade de pointes, is a major concern with use of many medications, including for non-cardiac conditions. The possibility that genetic risk, in...
10.
Stoneman H, Price A, Trout N, Lamont R, Tifour S, Pozdeyev N, et al.
bioRxiv
. 2024 May;
PMID: 38766180
Genetic summary data are broadly accessible and highly useful including for risk prediction, causal inference, fine mapping, and incorporation of external controls. However, collapsing individual-level data into groups masks intra-...