Christopher M Roundy
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Explore the profile of Christopher M Roundy including associated specialties, affiliations and a list of published articles.
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24
Citations
1035
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Recent Articles
11.
Kozlova E, Hegde S, Roundy C, Golovko G, Saldana M, Hart C, et al.
ISME J
. 2020 Sep;
15(1):93-108.
PMID: 32895494
How microbe-microbe interactions dictate microbial complexity in the mosquito gut is unclear. Previously we found that, Serratia, a gut symbiont that alters vector competence and is being considered for vector...
12.
ZIKV Demonstrates Minimal Pathologic Effects and Mosquito Infectivity in Viremic Cynomolgus Macaques
Azar S, Rossi S, Haller S, Yun R, Huang J, Plante J, et al.
Viruses
. 2018 Nov;
10(11).
PMID: 30469417
To evaluate the effects of ZIKV infection on non-human primates (NHPs), as well as to investigate whether these NHPs develop sufficient viremia to infect the major urban vector mosquito, ,...
13.
Vanchiere J, Ruiz J, Brady A, Kuehl T, Williams L, Baze W, et al.
Am J Trop Med Hyg
. 2017 Nov;
98(1):173-177.
PMID: 29182145
The establishment of a sylvatic reservoir of Zika virus (ZIKV) in the Americas is dependent on the susceptibility of primates of sufficient population density, the duration and magnitude of viremia,...
14.
Fontes-Garfias C, Shan C, Luo H, Muruato A, Medeiros D, Mays E, et al.
Cell Rep
. 2017 Nov;
21(5):1180-1190.
PMID: 29091758
Zika virus (ZIKV) infection causes devastating congenital abnormities and Guillain-Barré syndrome. The ZIKV envelope (E) protein is responsible for viral entry and represents a major determinant for viral pathogenesis. Like...
15.
Roundy C, Azar S, Brault A, Ebel G, Failloux A, Fernandez-Salas I, et al.
Emerg Microbes Infect
. 2017 Oct;
6(10):e90.
PMID: 29044195
No abstract available.
16.
Azar S, Roundy C, Rossi S, Huang J, Leal G, Yun R, et al.
Am J Trop Med Hyg
. 2017 Aug;
97(2):330-339.
PMID: 28829735
To evaluate the potential role of s (Skuse) as a vector of Zika virus (ZIKV), colonized mosquitoes of low generation number (≤ F5) from Brazil, Houston, and the Rio Grande...
17.
Langsjoen R, Auguste A, Rossi S, Roundy C, Penate H, Kastis M, et al.
Antiviral Res
. 2017 May;
143:246-251.
PMID: 28461071
Alphaviruses require conserved cysteine residues for proper folding and assembly of the E1 and E2 envelope glycoproteins, and likely depend on host protein disulfide isomerase-family enzymes (PDI) to aid in...
18.
Roundy C, Azar S, Rossi S, Weaver S, Vasilakis N
Adv Virus Res
. 2017 Apr;
98:119-146.
PMID: 28433051
Arthropod-borne viruses (arboviruses) have in recent years become a tremendous global health concern resulting in substantial human morbidity and mortality. With the widespread utilization of molecular technologies such as next-generation...
19.
Roundy C, Azar S, Rossi S, Huang J, Leal G, Yun R, et al.
Emerg Infect Dis
. 2017 Mar;
23(4):625-632.
PMID: 28287375
To test whether Zika virus has adapted for more efficient transmission by Aedes aegypti mosquitoes, leading to recent urban outbreaks, we fed mosquitoes from Brazil, the Dominican Republic, and the...
20.
McGrath E, Rossi S, Gao J, Widen S, Grant A, Dunn T, et al.
Stem Cell Reports
. 2017 Feb;
8(3):715-727.
PMID: 28216147
Zika virus (ZIKV) infection causes microcephaly in a subset of infants born to infected pregnant mothers. It is unknown whether human individual differences contribute to differential susceptibility of ZIKV-related neuropathology....