Christopher J Walkey
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Explore the profile of Christopher J Walkey including associated specialties, affiliations and a list of published articles.
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21
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821
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Recent Articles
11.
Doerfler A, Walkey C, Lagor W
Curr Opin Cardiol
. 2020 Feb;
35(3):242-248.
PMID: 32073405
Purpose Of Review: This review highlights recent progress in applying genome editing to the study and treatment of cardiovascular disease (CVD). Recent Findings: Recent work has shown that genome editing...
12.
Wang X, Walkey C, Maretti-Mira A, Wang L, Johnson D, DeLeve L
Hepatology
. 2020 Feb;
72(5):1771-1785.
PMID: 32060938
Background And Aims: This study examined whether enhanced susceptibility of steatotic liver to ischemia-reperfusion (I/R) injury is due to impaired recruitment of bone marrow (BM) progenitors of liver sinusoidal endothelial...
13.
Wang X, Rusin A, Walkey C, Lin J, Johnson D
J Biol Chem
. 2019 Oct;
294(50):19255-19268.
PMID: 31645432
MAF1 homolog, negative regulator of RNA polymerase III (MAF1) is a key repressor of RNA polymerase (pol) III-dependent transcription and functions as a tumor suppressor. Its expression is frequently down-regulated...
14.
Chen C, Lanz R, Walkey C, Chang W, Lu W, Johnson D
Cell Rep
. 2018 Aug;
24(7):1852-1864.
PMID: 30110641
RNA polymerase (pol) III transcribes a variety of small untranslated RNAs involved in transcription, RNA processing, and translation. RNA pol III and its components are altered in various human developmental...
15.
Johnson S, Lin J, Walkey C, Leathers M, Coarfa C, Johnson D
Oncotarget
. 2017 Apr;
8(30):48832-48845.
PMID: 28415573
The TATA-binding protein (TBP) plays a central role in eukaryotic gene transcription. Given its key function in transcription initiation, TBP was initially thought to be an invariant protein. However, studies...
16.
Palmer E, Jarrett K, Sachdev R, Zahrani F, Hashem M, Ibrahim N, et al.
Hum Mol Genet
. 2016 Jun;
25(14):3042-3054.
PMID: 27270415
We report an individual who presented with severe neurodevelopmental delay and an intractable infantile-onset seizure disorder. Exome sequencing identified a homozygous single nucleotide change that abolishes a splice donor site...
17.
Liu Y, Walkey C, Green T, van Vuuren H, Kitts D
Food Chem
. 2015 Oct;
194:26-31.
PMID: 26471523
Folate deficiency is linked to many diseases, some of which may have higher probability in individuals with alcohol-induced alterations in one-carbon metabolism. Our study shows that folate content in commercial...
18.
Bessonov K, Walkey C, Shelp B, van Vuuren H, Chiu D, van der Merwe G
PLoS One
. 2013 Oct;
8(10):e77192.
PMID: 24130853
Analyzing time-course expression data captured in microarray datasets is a complex undertaking as the vast and complex data space is represented by a relatively low number of samples as compared...
19.
Luo Z, Walkey C, Madilao L, Measday V, van Vuuren H
FEMS Yeast Res
. 2013 May;
13(5):485-94.
PMID: 23692528
Control of volatile acidity (VA) is a major issue for wine quality. In this study, we investigated the production of VA by a deletion mutant of the fermentation stress response...
20.
Walkey C, Luo Z, Madilao L, van Vuuren H
PLoS One
. 2012 Dec;
7(12):e51551.
PMID: 23240040
The production of acetic acid during wine fermentation is a critical issue for wineries since the sensory quality of a wine can be affected by the amount of acetic acid...