Christopher J B Nicol
Overview
Explore the profile of Christopher J B Nicol including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
222
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Recent Articles
1.
Chiang M, Yang Y, Nicol C, Chiang T, Yen C
Life (Basel)
. 2025 Feb;
15(2).
PMID: 40003703
Parkinson's disease (PD) is a progressive neurodegenerative disorder primarily characterized by the loss of dopaminergic neurons in the substantia nigra. Mitochondrial dysfunction, oxidative stress, and neuroinflammation are recognized as critical...
2.
Chiang M, Nicol C, Yang Y, Chiang T, Yen C
Brain Res
. 2025 Feb;
1852:149506.
PMID: 39954799
Alzheimer's disease (AD) is the primary cause of dementia in older adults. Amyloid-beta (Aβ) and tau protein neurofibrillary tangles accumulate in the brain, leading to a progressive decline in memory,...
3.
Chiang M, Nicol C, Yang Y, Chiang T, Yen C
Neuroscience
. 2025 Feb;
569:67-84.
PMID: 39909340
Background: Exposure to PM is associated with neurotoxicity and mitochondrial dysfunction. Resveratrol, a natural polyphenol, has demonstrated antioxidant and neuroprotective properties. Still, its efficacy in mitigating PM-induced damage in human...
4.
Sarmasti Emami S, Ge A, Zhang D, Hao Y, Ling M, Rubino R, et al.
Int J Mol Sci
. 2024 Apr;
25(7).
PMID: 38612874
The Hippo pathway plays crucial roles in governing various biological processes during tumorigenesis and metastasis. Within this pathway, upstream signaling stimuli activate a core kinase cascade, involving MST1/2 and LATS1/2,...
5.
Chiang M, Yang Y, Nicol C, Wang C
Int J Mol Sci
. 2024 Feb;
25(4).
PMID: 38397037
This review explores the diverse applications of gold nanoparticles (AuNPs) in neurological diseases, with a specific focus on Alzheimer's disease (AD), Parkinson's disease (PD), and stroke. The introduction highlights the...
6.
Tomalty D, Giovannetti O, Velikonja L, Munday J, Kaufmann M, Iaboni N, et al.
J Anat
. 2023 Jun;
243(5):758-769.
PMID: 37264225
Desorption electrospray ionization mass spectrometry imaging (DESI-MSI) is a molecular imaging method that can be used to elucidate the small-molecule composition of tissues and map their spatial information using two-dimensional...
7.
Kaufmann M, Iaboni N, Jamzad A, Hurlbut D, Ren K, Rudan J, et al.
Metabolites
. 2023 Apr;
13(4).
PMID: 37110166
Colorectal cancer (CRC) is the second leading cause of cancer deaths. Despite recent advances, five-year survival rates remain largely unchanged. Desorption electrospray ionization mass spectrometry imaging (DESI) is an emerging...
8.
Hoskin V, Ghaffari A, Laight B, SenGupta S, Madarnas Y, Nicol C, et al.
Cancer Res Commun
. 2023 Mar;
2(6):456-470.
PMID: 36923551
Significance: This work provides preclinical evidence for combining anti-ezrin treatment with chemotherapy as a novel strategy for effectively targeting metastasis, particularly in a neoadjuvant treatment setting.
9.
Chiang M, Nicol C, Lo S, Hung S, Wang C, Lin C
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232980
Oxygen glucose deprivation (OGD) can produce hypoxia-induced neurotoxicity and is a mature in vitro model of hypoxic cell damage. Activated AMP-activated protein kinase (AMPK) regulates a downstream pathway that substantially...
10.
Chiang M, Nicol C
Free Radic Biol Med
. 2022 Jun;
187:185-201.
PMID: 35660451
Amyloid-beta (Aβ) peptides have a role in the pathogenesis of Alzheimer's disease (AD) and are thought to promote oxidative stress, endoplasmic reticulum (ER) stress and mitochondrial deficiency, causing neuronal loss...