Christopher Hennecker
Overview
Explore the profile of Christopher Hennecker including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
61
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0
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Recent Articles
1.
El-Khoury R, Macaluso V, Hennecker C, Mittermaier A, Orozco M, Gonzalez C, et al.
Commun Chem
. 2023 Feb;
6(1):31.
PMID: 36797370
G-quadruplex and i-motif nucleic acid structures are believed to fold through kinetic partitioning mechanisms. Such mechanisms explain the structural heterogeneity of G-quadruplex metastable intermediates which have been extensively reported. On...
2.
Hennecker C, Yamout L, Zhang C, Zhao C, Hiraki D, Moitessier N, et al.
Int J Mol Sci
. 2022 Dec;
23(24).
PMID: 36555662
Intramolecular guanine quadruplexes (G4s) are non-canonical nucleic acid structures formed by four guanine (G)-rich tracts that assemble into a core of stacked planar tetrads. G4-forming DNA sequences are enriched in...
3.
Stille J, Tjutrins J, Wang G, Venegas F, Hennecker C, Rueda A, et al.
Eur J Med Chem
. 2022 Jan;
229:114046.
PMID: 34995923
Severe diseases such as the ongoing COVID-19 pandemic, as well as the previous SARS and MERS outbreaks, are the result of coronavirus infections and have demonstrated the urgent need for...
4.
Harkness R, Hennecker C, Grun J, Blumler A, Heckel A, Schwalbe H, et al.
Nucleic Acids Res
. 2021 Jan;
49(3):1247-1262.
PMID: 33469659
G-quadruplexes (G4s) are four-stranded, guanine-rich nucleic acid structures that can influence a variety of biological processes such as the transcription and translation of genes and DNA replication. In many cases,...
5.
Prinzen A, Saliba D, Hennecker C, Trinh T, Mittermaier A, Sleiman H
Angew Chem Int Ed Engl
. 2020 Apr;
59(31):12900-12908.
PMID: 32277788
Triggering the release of small molecules in response to unique biomarkers is important for applications in drug delivery and biodetection. Due to low quantities of biomarker, amplifying release is necessary...
6.
Grun J, Hennecker C, Klotzner D, Harkness R, Bessi I, Heckel A, et al.
J Am Chem Soc
. 2019 Dec;
142(1):264-273.
PMID: 31815451
The complex folding energy landscape of DNA G-quadruplexes leads to numerous conformations for this functionally important class of noncanonical DNA structures. A new layer of conformational heterogeneity comes from sequences...