Christopher Dean Goodman
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Explore the profile of Christopher Dean Goodman including associated specialties, affiliations and a list of published articles.
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10
Citations
351
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Recent Articles
1.
Dans M, Boulet C, Watson G, Nguyen W, Dziekan J, Evelyn C, et al.
Nat Commun
. 2024 Sep;
15(1):8459.
PMID: 39349462
No abstract available.
2.
Dans M, Boulet C, Watson G, Nguyen W, Dziekan J, Evelyn C, et al.
Nat Commun
. 2024 Jun;
15(1):5219.
PMID: 38890312
With resistance to most antimalarials increasing, it is imperative that new drugs are developed. We previously identified an aryl acetamide compound, MMV006833 (M-833), that inhibited the ring-stage development of newly...
3.
Dans M, Piirainen H, Nguyen W, Khurana S, Mehra S, Razook Z, et al.
PLoS Biol
. 2023 Apr;
21(4):e3002066.
PMID: 37053271
With emerging resistance to frontline treatments, it is vital that new antimalarial drugs are identified to target Plasmodium falciparum. We have recently described a compound, MMV020291, as a specific inhibitor...
4.
Goodman C, Hoang A, Diallo D, Malterud K, McFadden G, Wangensteen H
Planta Med
. 2019 Aug;
85(13):1073-1079.
PMID: 31365939
, syn. , is a tree growing in West Africa and is used in traditional medicine against a variety of diseases, including malaria. In the work reported here, root bark...
5.
Uddin T, McFadden G, Goodman C
Antimicrob Agents Chemother
. 2017 Nov;
62(1).
PMID: 29109165
Malaria parasites contain a relict plastid, the apicoplast, which is considered an excellent drug target due to its bacterial-like ancestry. Numerous parasiticidals have been proposed to target the apicoplast, but...
6.
Goodman C, Austarheim I, Mollard V, Mikolo B, Malterud K, McFadden G, et al.
Malar J
. 2016 Nov;
15(1):560.
PMID: 27855676
No abstract available.
7.
Goodman C, Austarheim I, Mollard V, Mikolo B, Malterud K, McFadden G, et al.
Malar J
. 2016 Sep;
15:481.
PMID: 27649682
Background: Zanthoxylum heitzii (Rutaceae) (olon) is used in traditional medicine in Central and West Africa to treat malaria. To identify novel compounds with anti-parasitic activity and validate medicinal usage, extracts...
8.
Smith C, Jerkovic A, Puy H, Winship I, Deybach J, Gouya L, et al.
Blood
. 2014 Nov;
125(3):534-41.
PMID: 25414439
Many red cell polymorphisms are a result of selective pressure by the malarial parasite. Here, we add another red cell disease to the panoply of erythrocytic changes that give rise...
9.
Goodman C, Su V, McFadden G
Mol Biochem Parasitol
. 2007 Feb;
152(2):181-91.
PMID: 17289168
Many anti-bacterial drugs inhibit growth of malaria parasites by targeting their bacterium-derived endosymbiotic organelles, the mitochondrion and plastid. Several of these drugs are either in use or being developed as...
10.
Goodman C, Casati P, Walbot V
Plant Cell
. 2004 Jun;
16(7):1812-26.
PMID: 15208386
Anthocyanin biosynthesis is one of the most thoroughly studied enzymatic pathways in biology, but little is known about the molecular mechanisms of its final stage: the transport of the anthocyanin...