Niall D Geoghegan
Overview
Explore the profile of Niall D Geoghegan including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
840
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Atkin-Smith G, Santavanond J, Light A, Rimes J, Samson A, Er J, et al.
Nat Commun
. 2024 Oct;
15(1):8802.
PMID: 39438460
Endothelial cells are integral components of all vasculature within complex organisms. As they line the blood vessel wall, endothelial cells are constantly exposed to a variety of molecular factors and...
2.
Dans M, Boulet C, Watson G, Nguyen W, Dziekan J, Evelyn C, et al.
Nat Commun
. 2024 Sep;
15(1):8459.
PMID: 39349462
No abstract available.
3.
Dans M, Boulet C, Watson G, Nguyen W, Dziekan J, Evelyn C, et al.
Nat Commun
. 2024 Jun;
15(1):5219.
PMID: 38890312
With resistance to most antimalarials increasing, it is imperative that new drugs are developed. We previously identified an aryl acetamide compound, MMV006833 (M-833), that inhibited the ring-stage development of newly...
4.
Liang L, Geoghegan N, Mlodzianoski M, Leis A, Whitehead L, Surudoi M, et al.
Commun Biol
. 2024 Apr;
7(1):461.
PMID: 38627519
EphB6 is an understudied ephrin receptor tyrosine pseudokinase that is downregulated in multiple types of metastatic cancers. Unlike its kinase-active counterparts which autophosphorylate and transmit signals upon intercellular interaction, little...
5.
Bergamasco M, Vanyai H, Garnham A, Geoghegan N, Vogel A, Eccles S, et al.
J Clin Invest
. 2024 Apr;
134(7).
PMID: 38557491
Mutations in genes encoding chromatin modifiers are enriched among mutations causing intellectual disability. The continuing development of the brain postnatally, coupled with the inherent reversibility of chromatin modifications, may afford...
6.
Hawdon A, Geoghegan N, Mohenska M, Elsenhans A, Ferguson C, Polo J, et al.
Nat Commun
. 2023 May;
14(1):2909.
PMID: 37253716
The spatial sorting of RNA transcripts is fundamental for the refinement of gene expression to distinct subcellular regions. Although, in non-mammalian early embryogenesis, differential RNA localisation presages cell fate determination,...
7.
Dans M, Piirainen H, Nguyen W, Khurana S, Mehra S, Razook Z, et al.
PLoS Biol
. 2023 Apr;
21(4):e3002066.
PMID: 37053271
With emerging resistance to frontline treatments, it is vital that new antimalarial drugs are identified to target Plasmodium falciparum. We have recently described a compound, MMV020291, as a specific inhibitor...
8.
Scally S, Triglia T, Evelyn C, Seager B, Pasternak M, Lim P, et al.
Nat Microbiol
. 2022 Nov;
7(12):2039-2053.
PMID: 36396942
The most severe form of malaria is caused by Plasmodium falciparum. These parasites invade human erythrocytes, and an essential step in this process involves the ligand PfRh5, which forms a...
9.
Gan Z, Callegari S, Cobbold S, Cotton T, Mlodzianoski M, Schubert A, et al.
Nature
. 2022 Mar;
603(7903):E33.
PMID: 35293391
No abstract available.
10.
Davidson S, Yu C, Steiner A, Ebstein F, Baker P, Jarur-Chamy V, et al.
Sci Immunol
. 2022 Feb;
7(68):eabi6763.
PMID: 35148201
Proteasome dysfunction can lead to autoinflammatory disease associated with elevated type I interferon (IFN-αβ) and NF-κB signaling; however, the innate immune pathway driving this is currently unknown. Here, we identified...